1pha: Difference between revisions

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[[Image:1pha.gif|left|200px]]<br /><applet load="1pha" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1pha.gif|left|200px]]
caption="1pha, resolution 1.63&Aring;" />
 
'''INHIBITOR-INDUCED CONFORMATIONAL CHANGE IN CYTOCHROME P450-CAM'''<br />
{{Structure
|PDB= 1pha |SIZE=350|CAPTION= <scene name='initialview01'>1pha</scene>, resolution 1.63&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene> and <scene name='pdbligand=PFZ:1-(N-IMIDAZOLYL)-2-HYDROXY-2-(2,3-DICHLOROPHENYL)OCTANE'>PFZ</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Camphor_5-monooxygenase Camphor 5-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.1 1.14.15.1]
|GENE=
}}
 
'''INHIBITOR-INDUCED CONFORMATIONAL CHANGE IN CYTOCHROME P450-CAM'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1PHA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida] with <scene name='pdbligand=HEM:'>HEM</scene> and <scene name='pdbligand=PFZ:'>PFZ</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Camphor_5-monooxygenase Camphor 5-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.1 1.14.15.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PHA OCA].  
1PHA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PHA OCA].  


==Reference==
==Reference==
Inhibitor-induced conformational change in cytochrome P-450CAM., Raag R, Li H, Jones BC, Poulos TL, Biochemistry. 1993 May 4;32(17):4571-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8485133 8485133]
Inhibitor-induced conformational change in cytochrome P-450CAM., Raag R, Li H, Jones BC, Poulos TL, Biochemistry. 1993 May 4;32(17):4571-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8485133 8485133]
[[Category: Camphor 5-monooxygenase]]
[[Category: Camphor 5-monooxygenase]]
[[Category: Pseudomonas putida]]
[[Category: Pseudomonas putida]]
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[[Category: oxidoreductase(oxygenase)]]
[[Category: oxidoreductase(oxygenase)]]


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