1pho: Difference between revisions
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[[Image:1pho.gif|left|200px]] | [[Image:1pho.gif|left|200px]] | ||
'''CRYSTAL STRUCTURES EXPLAIN FUNCTIONAL PROPERTIES OF TWO E. COLI PORINS''' | {{Structure | ||
|PDB= 1pho |SIZE=350|CAPTION= <scene name='initialview01'>1pho</scene>, resolution 3.0Å | |||
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'''CRYSTAL STRUCTURES EXPLAIN FUNCTIONAL PROPERTIES OF TWO E. COLI PORINS''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1PHO is a [ | 1PHO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PHO OCA]. | ||
==Reference== | ==Reference== | ||
Crystal structures explain functional properties of two E. coli porins., Cowan SW, Schirmer T, Rummel G, Steiert M, Ghosh R, Pauptit RA, Jansonius JN, Rosenbusch JP, Nature. 1992 Aug 27;358(6389):727-33. PMID:[http:// | Crystal structures explain functional properties of two E. coli porins., Cowan SW, Schirmer T, Rummel G, Steiert M, Ghosh R, Pauptit RA, Jansonius JN, Rosenbusch JP, Nature. 1992 Aug 27;358(6389):727-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1380671 1380671] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: outer membrane protein]] | [[Category: outer membrane protein]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:24:31 2008'' | ||
Revision as of 11:24, 20 March 2008
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| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
CRYSTAL STRUCTURES EXPLAIN FUNCTIONAL PROPERTIES OF TWO E. COLI PORINS
Overview
Porins form aqueous channels that aid the diffusion of small hydrophilic molecules across the outer membrane of Gram-negative bacteria. The crystal structures of matrix porin and phosphoporin both reveal trimers of identical subunits, each subunit consisting of a 16-stranded anti-parallel beta-barrel containing a pore. A long loop inside the barrel contributes to a constriction of the channel where the charge distribution affects ion selectivity. The structures explain at the molecular level functional characteristics and their alterations by known mutations.
About this Structure
1PHO is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Crystal structures explain functional properties of two E. coli porins., Cowan SW, Schirmer T, Rummel G, Steiert M, Ghosh R, Pauptit RA, Jansonius JN, Rosenbusch JP, Nature. 1992 Aug 27;358(6389):727-33. PMID:1380671
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