2mdk: Difference between revisions
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==NMR Solution Structure of MSP-P56S Domain/VAPB in DPC== | |||
<StructureSection load='2mdk' size='340' side='right' caption='[[2mdk]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | |||
== Structural highlights == | |||
==Disease== | <table><tr><td colspan='2'>[[2mdk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MDK FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VAPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mdk RCSB], [http://www.ebi.ac.uk/pdbsum/2mdk PDBsum]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN]] Adult-onset proximal spinal muscular atrophy, autosomal dominant;Amyotrophic lateral sclerosis. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | [[http://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN]] Adult-onset proximal spinal muscular atrophy, autosomal dominant;Amyotrophic lateral sclerosis. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN]] Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.<ref>PMID:16891305</ref> <ref>PMID:20940299</ref> <ref>PMID:22131369</ref> | [[http://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN]] Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.<ref>PMID:16891305</ref> <ref>PMID:20940299</ref> <ref>PMID:22131369</ref> | ||
== References == | |||
== | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
<references | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Lim, L | [[Category: Lim, L]] | ||
[[Category: Qin, H | [[Category: Qin, H]] | ||
[[Category: Song, J | [[Category: Song, J]] | ||
[[Category: Membrane protein]] | [[Category: Membrane protein]] | ||
[[Category: Msp-p56s domain]] | [[Category: Msp-p56s domain]] | ||
[[Category: Vapb]] | [[Category: Vapb]] | ||
Revision as of 11:27, 18 December 2014
NMR Solution Structure of MSP-P56S Domain/VAPB in DPC
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