1plo: Difference between revisions

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[[Image:1plo.gif|left|200px]]<br /><applet load="1plo" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1plo.gif|left|200px]]
caption="1plo" />
 
'''TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR EXTRACELLULAR DOMAIN'''<br />
{{Structure
|PDB= 1plo |SIZE=350|CAPTION= <scene name='initialview01'>1plo</scene>
|SITE=  
|LIGAND=  
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE= TGFBR2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR EXTRACELLULAR DOMAIN'''
 


==Overview==
==Overview==
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==Disease==
==Disease==
Known diseases associated with this structure: Aortic aneurysm, familial thoracic 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Colon cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Colorectal cancer, hereditary nonpolyposis, type 6 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Esophageal cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Loeys-Dietz syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Marfan syndrome, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]]
Known diseases associated with this structure: Colorectal cancer, hereditary nonpolyposis, type 6 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Esophageal cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Loeys-Dietz syndrome, type 1B OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Loeys-Dietz syndrome, type 2B OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]]


==About this Structure==
==About this Structure==
1PLO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PLO OCA].  
1PLO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PLO OCA].  


==Reference==
==Reference==
Solution structure and backbone dynamics of the TGFbeta type II receptor extracellular domain., Deep S, Walker KP 3rd, Shu Z, Hinck AP, Biochemistry. 2003 Sep 2;42(34):10126-39. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12939140 12939140]
Solution structure and backbone dynamics of the TGFbeta type II receptor extracellular domain., Deep S, Walker KP 3rd, Shu Z, Hinck AP, Biochemistry. 2003 Sep 2;42(34):10126-39. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12939140 12939140]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: three-finger toxin fold]]
[[Category: three-finger toxin fold]]


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Retrieved from "https://proteopedia.org/1plo"