2lx7: Difference between revisions
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==Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A== | |||
<StructureSection load='2lx7' size='340' side='right' caption='[[2lx7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |||
== Structural highlights == | |||
==Disease== | <table><tr><td colspan='2'>[[2lx7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LX7 FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GAS7, KIAA0394 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lx7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2lx7 PDBsum]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX. | [[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX. | ||
== Function == | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] May play a role in promoting maturation and morphological differentiation of cerebellar neurons. | [[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] May play a role in promoting maturation and morphological differentiation of cerebellar neurons. | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Acton, T | [[Category: Acton, T]] | ||
[[Category: Dan, L | [[Category: Dan, L]] | ||
[[Category: Everett, J K | [[Category: Everett, J K]] | ||
[[Category: Janjua, H | [[Category: Janjua, H]] | ||
[[Category: Kennedy, M A | [[Category: Kennedy, M A]] | ||
[[Category: Kohan, E | [[Category: Kohan, E]] | ||
[[Category: Montelione, G T | [[Category: Montelione, G T]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Ramelot, T A | [[Category: Ramelot, T A]] | ||
[[Category: Xiao, R | [[Category: Xiao, R]] | ||
[[Category: Yang, Y | [[Category: Yang, Y]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
[[Category: Protein structure initiative]] | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
[[Category: Target hr8574a]] | [[Category: Target hr8574a]] | ||
