1pwd: Difference between revisions

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[[Image:1pwd.jpg|left|200px]]<br /><applet load="1pwd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1pwd.jpg|left|200px]]
caption="1pwd, resolution 1.20&Aring;" />
 
'''Covalent acyl enzyme complex of the Streptomyces R61 DD-peptidase with cephalosporin C'''<br />
{{Structure
|PDB= 1pwd |SIZE=350|CAPTION= <scene name='initialview01'>1pwd</scene>, resolution 1.20&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CSC:4-(3-ACETOXYMETHYL-2-CARBOXY-8-OXO-5-THIA-1-AZA-BICYCLO[4.2.0]OCT-2-EN-7-YLCARBAMOYL)-1-CARBOXY-BUTYL-AMMONIUM'>CSC</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4]
|GENE=
}}
 
'''Covalent acyl enzyme complex of the Streptomyces R61 DD-peptidase with cephalosporin C'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1PWD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp. Streptomyces sp.] with <scene name='pdbligand=CSC:'>CSC</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PWD OCA].  
1PWD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp. Streptomyces sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PWD OCA].  


==Reference==
==Reference==
Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"., Silvaggi NR, Josephine HR, Kuzin AP, Nagarajan R, Pratt RF, Kelly JA, J Mol Biol. 2005 Jan 21;345(3):521-33. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15581896 15581896]
Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"., Silvaggi NR, Josephine HR, Kuzin AP, Nagarajan R, Pratt RF, Kelly JA, J Mol Biol. 2005 Jan 21;345(3):521-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15581896 15581896]
[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Silvaggi, N R.]]
[[Category: Silvaggi, N R.]]
[[Category: CSC]]
[[Category: CSC]]
[[Category: antibiotics]]
[[Category: antibiotic]]
[[Category: beta-lactam]]
[[Category: beta-lactam]]
[[Category: enzyme]]
[[Category: enzyme]]
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[[Category: peptidoglycan]]
[[Category: peptidoglycan]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:29:52 2008''
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