1px4: Difference between revisions

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[[Image:1px4.jpg|left|200px]]<br /><applet load="1px4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1px4.jpg|left|200px]]
caption="1px4, resolution 1.6&Aring;" />
 
'''E. COLI (LACZ) BETA-GALACTOSIDASE (G794A) WITH IPTG BOUND'''<br />
{{Structure
|PDB= 1px4 |SIZE=350|CAPTION= <scene name='initialview01'>1px4</scene>, resolution 1.6&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=IPT:ISOPROPYL-1-BETA-D-THIOGALACTOSIDE'>IPT</scene> and <scene name='pdbligand=DMS:DIMETHYL SULFOXIDE'>DMS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23]
|GENE= lacZ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''E. COLI (LACZ) BETA-GALACTOSIDASE (G794A) WITH IPTG BOUND'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1PX4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=IPT:'>IPT</scene> and <scene name='pdbligand=DMS:'>DMS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PX4 OCA].  
1PX4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PX4 OCA].  


==Reference==
==Reference==
Structural basis for the altered activity of Gly794 variants of Escherichia coli beta-galactosidase., Juers DH, Hakda S, Matthews BW, Huber RE, Biochemistry. 2003 Nov 25;42(46):13505-11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14621996 14621996]
Structural basis for the altered activity of Gly794 variants of Escherichia coli beta-galactosidase., Juers DH, Hakda S, Matthews BW, Huber RE, Biochemistry. 2003 Nov 25;42(46):13505-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14621996 14621996]
[[Category: Beta-galactosidase]]
[[Category: Beta-galactosidase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: loop conformation]]
[[Category: loop conformation]]


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