1pxg: Difference between revisions

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[[Image:1pxg.gif|left|200px]]<br /><applet load="1pxg" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1pxg.gif|left|200px]]
caption="1pxg, resolution 1.70&Aring;" />
 
'''Crystal structure of the mutated tRNA-guanine transglycosylase (TGT) D280E complexed with preQ1'''<br />
{{Structure
|PDB= 1pxg |SIZE=350|CAPTION= <scene name='initialview01'>1pxg</scene>, resolution 1.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=PRF:7-DEAZA-7-AMINOMETHYL-GUANINE'>PRF</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Queuine_tRNA-ribosyltransferase Queuine tRNA-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29]
|GENE= TGT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=542 Zymomonas mobilis])
}}
 
'''Crystal structure of the mutated tRNA-guanine transglycosylase (TGT) D280E complexed with preQ1'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1PXG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=PRF:'>PRF</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Queuine_tRNA-ribosyltransferase Queuine tRNA-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PXG OCA].  
1PXG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PXG OCA].  


==Reference==
==Reference==
An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coli., Kittendorf JD, Sgraja T, Reuter K, Klebe G, Garcia GA, J Biol Chem. 2003 Oct 24;278(43):42369-76. Epub 2003 Aug 8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12909636 12909636]
An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coli., Kittendorf JD, Sgraja T, Reuter K, Klebe G, Garcia GA, J Biol Chem. 2003 Oct 24;278(43):42369-76. Epub 2003 Aug 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12909636 12909636]
[[Category: Queuine tRNA-ribosyltransferase]]
[[Category: Queuine tRNA-ribosyltransferase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tim-barrel]]
[[Category: tim-barrel]]


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