1q3a: Difference between revisions

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[[Image:1q3a.jpg|left|200px]]<br /><applet load="1q3a" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1q3a.jpg|left|200px]]
caption="1q3a, resolution 2.10&Aring;" />
 
'''Crystal structure of the catalytic domain of human matrix metalloproteinase 10'''<br />
{{Structure
|PDB= 1q3a |SIZE=350|CAPTION= <scene name='initialview01'>1q3a</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=NGH:N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID'>NGH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Stromelysin_2 Stromelysin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.22 3.4.24.22]
|GENE= MMP10 OR STMY2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the catalytic domain of human matrix metalloproteinase 10'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1Q3A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=NGH:'>NGH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Stromelysin_2 Stromelysin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.22 3.4.24.22] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q3A OCA].  
1Q3A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q3A OCA].  


==Reference==
==Reference==
Crystal structure of the catalytic domain of human matrix metalloproteinase 10., Bertini I, Calderone V, Fragai M, Luchinat C, Mangani S, Terni B, J Mol Biol. 2004 Feb 20;336(3):707-16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15095982 15095982]
Crystal structure of the catalytic domain of human matrix metalloproteinase 10., Bertini I, Calderone V, Fragai M, Luchinat C, Mangani S, Terni B, J Mol Biol. 2004 Feb 20;336(3):707-16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15095982 15095982]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: ZN]]
[[Category: ZN]]
[[Category: hydroxamic acid]]
[[Category: hydroxamic acid]]
[[Category: inhibitors]]
[[Category: inhibitor]]
[[Category: metalloproteinase]]
[[Category: metalloproteinase]]
[[Category: mmp-10]]
[[Category: mmp-10]]
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[[Category: stromelysin-2]]
[[Category: stromelysin-2]]


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