1q3g: Difference between revisions

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[[Image:1q3g.gif|left|200px]]<br /><applet load="1q3g" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1q3g.gif|left|200px]]
caption="1q3g, resolution 2.65&Aring;" />
 
'''MurA (Asp305Ala) liganded with tetrahedral reaction intermediate'''<br />
{{Structure
|PDB= 1q3g |SIZE=350|CAPTION= <scene name='initialview01'>1q3g</scene>, resolution 2.65&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=UDA:3'-1-CARBOXY-1-PHOSPHONOOXY-ETHOXY-URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UDA</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7]
|GENE= MURA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=550 Enterobacter cloacae])
}}
 
'''MurA (Asp305Ala) liganded with tetrahedral reaction intermediate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1Q3G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae] with <scene name='pdbligand=UDA:'>UDA</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q3G OCA].  
1Q3G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q3G OCA].  


==Reference==
==Reference==
A new view of the mechanisms of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-phosphate synthase (AroA) derived from X-ray structures of their tetrahedral reaction intermediate states., Eschenburg S, Kabsch W, Healy ML, Schonbrunn E, J Biol Chem. 2003 Dec 5;278(49):49215-22. Epub 2003 Sep 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=13129913 13129913]
A new view of the mechanisms of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-phosphate synthase (AroA) derived from X-ray structures of their tetrahedral reaction intermediate states., Eschenburg S, Kabsch W, Healy ML, Schonbrunn E, J Biol Chem. 2003 Dec 5;278(49):49215-22. Epub 2003 Sep 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/13129913 13129913]
[[Category: Enterobacter cloacae]]
[[Category: Enterobacter cloacae]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: inside-out alpha-beta barrel]]
[[Category: inside-out alpha-beta barrel]]


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