1q4n: Difference between revisions

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[[Image:1q4n.gif|left|200px]]<br /><applet load="1q4n" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1q4n.gif|left|200px]]
caption="1q4n, resolution 2.07&Aring;" />
 
'''Structural studies of Phe256Trp of human salivary alpha-amylase: implications for the role of a conserved water molecule and its associated chain in enzyme activity'''<br />
{{Structure
|PDB= 1q4n |SIZE=350|CAPTION= <scene name='initialview01'>1q4n</scene>, resolution 2.07&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=TAM:TRIS(HYDROXYETHYL)AMINOMETHANE'>TAM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1]
|GENE= AMY1A OR AMY1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structural studies of Phe256Trp of human salivary alpha-amylase: implications for the role of a conserved water molecule and its associated chain in enzyme activity'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1Q4N is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=TAM:'>TAM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q4N OCA].  
1Q4N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q4N OCA].  


==Reference==
==Reference==
Structural studies of a Phe256Trp mutant of human salivary alpha-amylase: implications for the role of a conserved water molecule in enzyme activity., Ramasubbu N, Sundar K, Ragunath C, Rafi MM, Arch Biochem Biophys. 2004 Jan 1;421(1):115-24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14678792 14678792]
Structural studies of a Phe256Trp mutant of human salivary alpha-amylase: implications for the role of a conserved water molecule in enzyme activity., Ramasubbu N, Sundar K, Ragunath C, Rafi MM, Arch Biochem Biophys. 2004 Jan 1;421(1):115-24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14678792 14678792]
[[Category: Alpha-amylase]]
[[Category: Alpha-amylase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: inhibitor]]
[[Category: inhibitor]]
[[Category: mutagenesis]]
[[Category: mutagenesis]]
[[Category: tris]]
[[Category: tri]]


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