3l07: Difference between revisions

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{{STRUCTURE_3l07|  PDB=3l07  |  SCENE=  }}
==Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase, putative bifunctional protein folD from Francisella tularensis.==
===Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase, putative bifunctional protein folD from Francisella tularensis.===
<StructureSection load='3l07' size='340' side='right' caption='[[3l07]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[3l07]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Francisella_tularensis Francisella tularensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L07 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L07 FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/FOLD_FRATW FOLD_FRATW]] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate (By similarity).  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folD, FTW_1287 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=263 Francisella tularensis])</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l07 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l07 RCSB], [http://www.ebi.ac.uk/pdbsum/3l07 PDBsum]</span></td></tr>
[[3l07]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Francisella_tularensis Francisella tularensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L07 OCA].  
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l0/3l07_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Francisella tularensis]]
[[Category: Francisella tularensis]]
[[Category: Anderson, W F.]]
[[Category: Anderson, W F]]
[[Category: Hasseman, J.]]
[[Category: Hasseman, J]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak, A]]
[[Category: Maltseva, N.]]
[[Category: Maltseva, N]]
[[Category: Mulligan, R.]]
[[Category: Mulligan, R]]
[[Category: Osipiuk, J.]]
[[Category: Osipiuk, J]]
[[Category: Amino-acid biosynthesis]]
[[Category: Amino-acid biosynthesis]]
[[Category: Bifunctional protein]]
[[Category: Bifunctional protein]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Structural genomic]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Histidine biosynthesis]]
[[Category: Histidine biosynthesis]]
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Purine biosynthesis]]
[[Category: Purine biosynthesis]]
[[Category: Structural genomic]]

Revision as of 14:43, 18 December 2014

Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase, putative bifunctional protein folD from Francisella tularensis.

3l07, resolution 1.88Å

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