1q7a: Difference between revisions

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[[Image:1q7a.jpg|left|200px]]<br /><applet load="1q7a" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1q7a.jpg|left|200px]]
caption="1q7a, resolution 1.6&Aring;" />
 
'''Crystal structure of the complex formed between russell's viper phospholipase A2 and an antiinflammatory agent oxyphenbutazone at 1.6A resolution'''<br />
{{Structure
|PDB= 1q7a |SIZE=350|CAPTION= <scene name='initialview01'>1q7a</scene>, resolution 1.6&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=OPB:4-BUTYL-1-(4-HYDROXYPHENYL)-2-PHENYLPYRAZOLIDINE-3,5-DIONE'>OPB</scene> and <scene name='pdbligand=MOH:METHANOL'>MOH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4]
|GENE=
}}
 
'''Crystal structure of the complex formed between russell's viper phospholipase A2 and an antiinflammatory agent oxyphenbutazone at 1.6A resolution'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1Q7A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Daboia_russellii_russellii Daboia russellii russellii] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=OPB:'>OPB</scene> and <scene name='pdbligand=MOH:'>MOH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q7A OCA].  
1Q7A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Daboia_russellii_russellii Daboia russellii russellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q7A OCA].  


==Reference==
==Reference==
Phospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution., Singh N, Jabeen T, Somvanshi RK, Sharma S, Dey S, Singh TP, Biochemistry. 2004 Nov 23;43(46):14577-83. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15544328 15544328]
Phospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution., Singh N, Jabeen T, Somvanshi RK, Sharma S, Dey S, Singh TP, Biochemistry. 2004 Nov 23;43(46):14577-83. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15544328 15544328]
[[Category: Daboia russellii russellii]]
[[Category: Daboia russellii russellii]]
[[Category: Phospholipase A(2)]]
[[Category: Phospholipase A(2)]]
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[[Category: venom]]
[[Category: venom]]


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