3n93: Difference between revisions

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~~{{STRUCTURE_3n93| PDB=3n93 | SCENE= }}~~

==Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3==

===Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3===

~~{{ABSTRACT_PUBMED_020966082}}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[3n93]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N93 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N93 FirstGlance].

==~~Function~~==

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAL:MALTOSE'>MAL</scene></td></tr>

[[~~http://www.uniprot.org/uniprot/UCN3_HUMAN UCN3_HUMAN~~]] ~~Suppresses food intake~~, ~~delays gastric emptying and decreases heat-induced edema~~. ~~Might represent an endogenous ligand for maintaining homeostasis after stress.~~

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[3n95|3n95]], [[3n96|3n96]]</td></tr>

==~~About this Structure~~==

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">CRFR2 alpha ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>

[[3n93]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N93 OCA].

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n93 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n93 RCSB], [http://www.ebi.ac.uk/pdbsum/3n93 PDBsum]</td></tr>

</table>

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Pal, K.]]

[[Category: Pal, K]]

[[Category: Pioszak, A A.]]

[[Category: Pioszak, A A]]

[[Category: Swaminathan, K.]]

[[Category: Swaminathan, K]]

[[Category: Xu, H E.]]

[[Category: Xu, H E]]

[[Category: Class b-gpcr]]

[[Category: Crfr2 alpha extracellular domain]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_3n93|  PDB=3n93  |  SCENE=  }}
+==Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3==
-===Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3===
+<StructureSection load='3n93' size='340' side='right' caption='[[3n93]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-{{ABSTRACT_PUBMED_020966082}}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3n93]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N93 FirstGlance]. <br>
-==Function==
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAL:MALTOSE'>MAL</scene></td></tr>
-[[http://www.uniprot.org/uniprot/UCN3_HUMAN UCN3_HUMAN]] Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3n95|3n95]], [[3n96|3n96]]</td></tr>
-==About this Structure==
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRFR2 alpha ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-[[3n93]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N93 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n93 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n93 RCSB], [http://www.ebi.ac.uk/pdbsum/3n93 PDBsum]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Pal, K.]]
+[[Category: Pal, K]]
-[[Category: Pioszak, A A.]]
+[[Category: Pioszak, A A]]
-[[Category: Swaminathan, K.]]
+[[Category: Swaminathan, K]]
-[[Category: Xu, H E.]]
+[[Category: Xu, H E]]
 [[Category: Class b-gpcr]]
 [[Category: Crfr2 alpha extracellular domain]]