1qca: Difference between revisions

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[[Image:1qca.jpg|left|200px]]<br /><applet load="1qca" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1qca.jpg|left|200px]]
caption="1qca, resolution 2.2&Aring;" />
 
'''QUADRUPLE MUTANT Q92C, N146F, Y168F, I172V TYPE III CAT COMPLEXED WITH FUSIDIC ACID. CRYSTALS GROWN AT PH 6.3. X-RAY DATA COLLECTED AT ROOM TEMPERATURE'''<br />
{{Structure
|PDB= 1qca |SIZE=350|CAPTION= <scene name='initialview01'>1qca</scene>, resolution 2.2&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene> and <scene name='pdbligand=FUA:FUSIDIC ACID'>FUA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Chloramphenicol_O-acetyltransferase Chloramphenicol O-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.28 2.3.1.28]
|GENE=
}}
 
'''QUADRUPLE MUTANT Q92C, N146F, Y168F, I172V TYPE III CAT COMPLEXED WITH FUSIDIC ACID. CRYSTALS GROWN AT PH 6.3. X-RAY DATA COLLECTED AT ROOM TEMPERATURE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1QCA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri] with <scene name='pdbligand=CO:'>CO</scene> and <scene name='pdbligand=FUA:'>FUA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Chloramphenicol_O-acetyltransferase Chloramphenicol O-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.28 2.3.1.28] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QCA OCA].  
1QCA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QCA OCA].  


==Reference==
==Reference==
Steroid recognition by chloramphenicol acetyltransferase: engineering and structural analysis of a high affinity fusidic acid binding site., Murray IA, Cann PA, Day PJ, Derrick JP, Sutcliffe MJ, Shaw WV, Leslie AG, J Mol Biol. 1995 Dec 15;254(5):993-1005. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7500366 7500366]
Steroid recognition by chloramphenicol acetyltransferase: engineering and structural analysis of a high affinity fusidic acid binding site., Murray IA, Cann PA, Day PJ, Derrick JP, Sutcliffe MJ, Shaw WV, Leslie AG, J Mol Biol. 1995 Dec 15;254(5):993-1005. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7500366 7500366]
[[Category: Chloramphenicol O-acetyltransferase]]
[[Category: Chloramphenicol O-acetyltransferase]]
[[Category: Shigella flexneri]]
[[Category: Shigella flexneri]]
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[[Category: steroid]]
[[Category: steroid]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:38:07 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:35:43 2008''
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