1qle: Difference between revisions

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[[Image:1qle.jpg|left|200px]]<br /><applet load="1qle" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1qle.jpg|left|200px]]
caption="1qle, resolution 3.0&Aring;" />
 
'''CRYO-STRUCTURE OF THE PARACOCCUS DENITRIFICANS FOUR-SUBUNIT CYTOCHROME C OXIDASE IN THE COMPLETELY OXIDIZED STATE COMPLEXED WITH AN ANTIBODY FV FRAGMENT'''<br />
{{Structure
|PDB= 1qle |SIZE=350|CAPTION= <scene name='initialview01'>1qle</scene>, resolution 3.0&Aring;
|SITE= <scene name='pdbsite=CA:Non+Redox+Active+Ca+Binding+Site'>CA</scene>, <scene name='pdbsite=CUA:Cu+A+Binding+Site'>CUA</scene>, <scene name='pdbsite=CUB:Cu+B+Binding+Site'>CUB</scene>, <scene name='pdbsite=HM3:Axial+Heme+A3+Ligand'>HM3</scene>, <scene name='pdbsite=HMA:Axial+Heme+A+Ligands'>HMA</scene> and <scene name='pdbsite=MM:Non+Redox+Active+Mn/Mg+Binding+Site'>MM</scene>
|LIGAND= <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=HEA:HEME-A'>HEA</scene>, <scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene> and <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1]
|GENE=
}}
 
'''CRYO-STRUCTURE OF THE PARACOCCUS DENITRIFICANS FOUR-SUBUNIT CYTOCHROME C OXIDASE IN THE COMPLETELY OXIDIZED STATE COMPLEXED WITH AN ANTIBODY FV FRAGMENT'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1QLE is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Paracoccus_denitrificans Paracoccus denitrificans] with <scene name='pdbligand=CU:'>CU</scene>, <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=HEA:'>HEA</scene>, <scene name='pdbligand=CUA:'>CUA</scene> and <scene name='pdbligand=PC1:'>PC1</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 1QLE with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb5_1.html Cytochrome c Oxidase]]. Active as [http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] Known structural/functional Sites: <scene name='pdbsite=CA:Non+Redox+Active+Ca+Binding+Site'>CA</scene>, <scene name='pdbsite=CUA:Cu+A+Binding+Site'>CUA</scene>, <scene name='pdbsite=CUB:Cu+B+Binding+Site'>CUB</scene>, <scene name='pdbsite=HM3:Axial+Heme+A3+Ligand'>HM3</scene>, <scene name='pdbsite=HMA:Axial+Heme+A+Ligands'>HMA</scene> and <scene name='pdbsite=MM:Non+Redox+Active+Mn/Mg+Binding+Site'>MM</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QLE OCA].  
1QLE is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Paracoccus_denitrificans Paracoccus denitrificans]. The following page contains interesting information on the relation of 1QLE with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb5_1.html Cytochrome c Oxidase]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QLE OCA].  


==Reference==
==Reference==
The cytochrome c oxidase from Paracoccus denitrificans does not change the metal center ligation upon reduction., Harrenga A, Michel H, J Biol Chem. 1999 Nov 19;274(47):33296-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10559205 10559205]
The cytochrome c oxidase from Paracoccus denitrificans does not change the metal center ligation upon reduction., Harrenga A, Michel H, J Biol Chem. 1999 Nov 19;274(47):33296-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10559205 10559205]
[[Category: Cytochrome c Oxidase]]
[[Category: Cytochrome c Oxidase]]
[[Category: Cytochrome-c oxidase]]
[[Category: Cytochrome-c oxidase]]
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[[Category: transmembrane]]
[[Category: transmembrane]]


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