3n8e: Difference between revisions

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{{STRUCTURE_3n8e|  PDB=3n8e  |  SCENE=  }}
==Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)==
===Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)===
<StructureSection load='3n8e' size='340' side='right' caption='[[3n8e]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[3n8e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N8E FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/GRP75_HUMAN GRP75_HUMAN]] Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRP75, HSPA9, HSPA9B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n8e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n8e RCSB], [http://www.ebi.ac.uk/pdbsum/3n8e PDBsum]</span></td></tr>
==About this Structure==
</table>
[[3n8e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8E OCA].  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n8/3n8e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H]]
[[Category: Berg, S van der.]]
[[Category: Berg, S van der]]
[[Category: Berglund, H.]]
[[Category: Berglund, H]]
[[Category: Bountra, C.]]
[[Category: Bountra, C]]
[[Category: Collins, R.]]
[[Category: Collins, R]]
[[Category: Edwards, A M.]]
[[Category: Edwards, A M]]
[[Category: Flodin, S.]]
[[Category: Flodin, S]]
[[Category: Flores, A.]]
[[Category: Flores, A]]
[[Category: Graslund, S.]]
[[Category: Graslund, S]]
[[Category: Hammarstrom, M.]]
[[Category: Hammarstrom, M]]
[[Category: Johansson, I.]]
[[Category: Johansson, I]]
[[Category: Karlberg, T.]]
[[Category: Karlberg, T]]
[[Category: Kotenyova, T.]]
[[Category: Kotenyova, T]]
[[Category: Moche, M.]]
[[Category: Moche, M]]
[[Category: Nordlund, P.]]
[[Category: Nordlund, P]]
[[Category: Nyman, T.]]
[[Category: Nyman, T]]
[[Category: Persson, C.]]
[[Category: Persson, C]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Structural genomic]]
[[Category: Schuler, H.]]
[[Category: Schuler, H]]
[[Category: Schutz, P.]]
[[Category: Schutz, P]]
[[Category: Siponen, M I.]]
[[Category: Siponen, M I]]
[[Category: Svensson, L.]]
[[Category: Svensson, L]]
[[Category: Thorsell, A G.]]
[[Category: Thorsell, A G]]
[[Category: Tresaugues, L.]]
[[Category: Tresaugues, L]]
[[Category: Wahlberg, E.]]
[[Category: Wahlberg, E]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J]]
[[Category: Welin, M.]]
[[Category: Welin, M]]
[[Category: Wisniewska, M.]]
[[Category: Wisniewska, M]]
[[Category: Beta-sandwich]]
[[Category: Beta-sandwich]]
[[Category: Chaperone]]
[[Category: Chaperone]]
[[Category: Helix]]
[[Category: Helix]]
[[Category: Sgc]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
[[Category: Substrate binding domain]]
[[Category: Substrate binding domain]]

Revision as of 17:41, 18 December 2014

Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)

3n8e, resolution 2.80Å

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