1qpr: Difference between revisions

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[[Image:1qpr.gif|left|200px]]<br /><applet load="1qpr" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1qpr.gif|left|200px]]
caption="1qpr, resolution 2.45&Aring;" />
 
'''QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP'''<br />
{{Structure
|PDB= 1qpr |SIZE=350|CAPTION= <scene name='initialview01'>1qpr</scene>, resolution 2.45&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PHT:PHTHALIC+ACID'>PHT</scene> and <scene name='pdbligand=PPC:5-PHOSPHORIBOSYL-1-(BETA-METHYLENE) PYROPHOSPHATE'>PPC</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Nicotinate-nucleotide_diphosphorylase_(carboxylating) Nicotinate-nucleotide diphosphorylase (carboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.19 2.4.2.19]
|GENE= NADC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
}}
 
'''QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1QPR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=PHT:'>PHT</scene> and <scene name='pdbligand=PPC:'>PPC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Nicotinate-nucleotide_diphosphorylase_(carboxylating) Nicotinate-nucleotide diphosphorylase (carboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.19 2.4.2.19] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QPR OCA].  
1QPR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QPR OCA].  


==Reference==
==Reference==
Crystal structure of quinolinic acid phosphoribosyltransferase from Mmycobacterium tuberculosis: a potential TB drug target., Sharma V, Grubmeyer C, Sacchettini JC, Structure. 1998 Dec 15;6(12):1587-99. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9862811 9862811]
Crystal structure of quinolinic acid phosphoribosyltransferase from Mmycobacterium tuberculosis: a potential TB drug target., Sharma V, Grubmeyer C, Sacchettini JC, Structure. 1998 Dec 15;6(12):1587-99. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9862811 9862811]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Nicotinate-nucleotide diphosphorylase (carboxylating)]]
[[Category: Nicotinate-nucleotide diphosphorylase (carboxylating)]]
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[[Category: psi]]
[[Category: psi]]
[[Category: quinolinic acid]]
[[Category: quinolinic acid]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: tb structural genomics consortium]]
[[Category: tb structural genomics consortium]]
[[Category: tbsgc]]
[[Category: tbsgc]]
[[Category: transferase]]
[[Category: transferase]]


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