3nqa: Difference between revisions

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{{STRUCTURE_3nqa|  PDB=3nqa  |  SCENE=  }}
==Crystal structure of the mutant F100A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP==
===Crystal structure of the mutant F100A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP===
<StructureSection load='3nqa' size='340' side='right' caption='[[3nqa]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[3nqa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NQA FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMP:6-HYDROXYURIDINE-5-PHOSPHATE'>BMP</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3g18|3g18]], [[3nq6|3nq6]], [[3nq7|3nq7]], [[3nqc|3nqc]], [[3nqd|3nqd]], [[3nqe|3nqe]], [[3nqf|3nqf]], [[3nqg|3nqg]], [[3nqm|3nqm]]</td></tr>
==About this Structure==
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrF, MTH_129 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=145262 Methanothermobacter thermautotrophicus])</td></tr>
[[3nqa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQA OCA].  
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nqa RCSB], [http://www.ebi.ac.uk/pdbsum/3nqa PDBsum]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Almo, S C.]]
[[Category: Almo, S C]]
[[Category: Fedorov, A A.]]
[[Category: Fedorov, A A]]
[[Category: Fedorov, E V.]]
[[Category: Fedorov, E V]]
[[Category: Gerlt, J A.]]
[[Category: Gerlt, J A]]
[[Category: Wood, B M.]]
[[Category: Wood, B M]]
[[Category: Inhibitor bmp]]
[[Category: Inhibitor bmp]]
[[Category: Lyase-lyase inhibitor complex]]
[[Category: Lyase-lyase inhibitor complex]]
[[Category: Methanobacterium thermoautotrophicum]]
[[Category: Methanobacterium thermoautotrophicum]]
[[Category: Orotidine 5'-monophosphate decarboxylase]]
[[Category: Orotidine 5'-monophosphate decarboxylase]]