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{{STRUCTURE_3opu|  PDB=3opu  |  SCENE=  }}
==Crystal structure of the C-terminal domain of Streptococcus mutans surface protein SpaP==
===Crystal structure of the C-terminal domain of Streptococcus mutans surface protein SpaP===
<StructureSection load='3opu' size='340' side='right' caption='[[3opu]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
{{ABSTRACT_PUBMED_21206016}}
== Structural highlights ==
<table><tr><td colspan='2'>[[3opu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OPU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SpaP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3opu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3opu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3opu RCSB], [http://www.ebi.ac.uk/pdbsum/3opu PDBsum]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
SpaP is a 1500-residue adhesin expressed on the surface of the caries-implicated bacterium Streptococcus mutans. SpaP is a member of the antigen I/II (AgI/II) family of proteins expressed by oral streptococci. These surface proteins are crucial for the incorporation of streptococci into dental plaque. The structure of the C-terminal domain of SpaP (residues 1136-1489) was solved and refined to 2.2 A resolution with six molecules in the asymmetric unit. Similar to a related AgI/II structure, SpaP is stabilized by isopeptide bonds between lysine and asparagine side chains.


==About this Structure==
Structure of the C-terminal domain of the surface antigen SpaP from the caries pathogen Streptococcus mutans.,Nylander A, Forsgren N, Persson K Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jan 1;67(Pt, 1):23-6. Epub 2010 Dec 21. PMID:21206016<ref>PMID:21206016</ref>
[[3opu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPU OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
<ref group="xtra">PMID:021206016</ref><references group="xtra"/><references/>
</div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Streptococcus mutans]]
[[Category: Streptococcus mutans]]
[[Category: Nylander, A.]]
[[Category: Nylander, A]]
[[Category: Persson, K.]]
[[Category: Persson, K]]
[[Category: Cell adhesion]]
[[Category: Cell adhesion]]
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