1qxd: Difference between revisions

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[[Image:1qxd.jpg|left|200px]]<br /><applet load="1qxd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1qxd.jpg|left|200px]]
caption="1qxd, resolution 2.25&Aring;" />
 
'''Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds'''<br />
{{Structure
|PDB= 1qxd |SIZE=350|CAPTION= <scene name='initialview01'>1qxd</scene>, resolution 2.25&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene> and <scene name='pdbligand=FU2:FURFURAL'>FU2</scene>
|ACTIVITY=
|GENE=
}}
 
'''Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1QXD is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=HEM:'>HEM</scene> and <scene name='pdbligand=FU2:'>FU2</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXD OCA].  
1QXD is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXD OCA].  


==Reference==
==Reference==
Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds., Safo MK, Abdulmalik O, Danso-Danquah R, Burnett JC, Nokuri S, Joshi GS, Musayev FN, Asakura T, Abraham DJ, J Med Chem. 2004 Sep 9;47(19):4665-76. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15341482 15341482]
Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds., Safo MK, Abdulmalik O, Danso-Danquah R, Burnett JC, Nokuri S, Joshi GS, Musayev FN, Asakura T, Abraham DJ, J Med Chem. 2004 Sep 9;47(19):4665-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15341482 15341482]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: allosteric; antisickling; relaxed state; hemoglobin; sickle cell; furfural]]
[[Category: allosteric; antisickling; relaxed state; hemoglobin; sickle cell; furfural]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:44:45 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:44:01 2008''
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