1r47: Difference between revisions

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[[Image:1r47.gif|left|200px]]<br /><applet load="1r47" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1r47.gif|left|200px]]
caption="1r47, resolution 3.45&Aring;" />
 
'''Structure of human alpha-galactosidase'''<br />
{{Structure
|PDB= 1r47 |SIZE=350|CAPTION= <scene name='initialview01'>1r47</scene>, resolution 3.45&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alpha-galactosidase Alpha-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.22 3.2.1.22]
|GENE= GLA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structure of human alpha-galactosidase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1R47 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=GAL:'>GAL</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alpha-galactosidase Alpha-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.22 3.2.1.22] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R47 OCA].  
1R47 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R47 OCA].  


==Reference==
==Reference==
The molecular defect leading to Fabry disease: structure of human alpha-galactosidase., Garman SC, Garboczi DN, J Mol Biol. 2004 Mar 19;337(2):319-35. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15003450 15003450]
The molecular defect leading to Fabry disease: structure of human alpha-galactosidase., Garman SC, Garboczi DN, J Mol Biol. 2004 Mar 19;337(2):319-35. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15003450 15003450]
[[Category: Alpha-galactosidase]]
[[Category: Alpha-galactosidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: lysosomal enzyme]]
[[Category: lysosomal enzyme]]


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