3q91: Difference between revisions

Line 1:

~~{{STRUCTURE_3q91| PDB=3q91 | SCENE= }}~~

==Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)==

===Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)===

== Structural highlights ==

==~~Function~~==

<table><tr><td colspan='2'>[[3q91]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q91 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q91 FirstGlance].

[[~~http://www.uniprot.org/uniprot/NUD14_HUMAN NUD14_HUMAN~~]] Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, ~~CDP-glucose, GDP-glucose and GDP-mannose~~.

</td></tr><tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[3q90|3q90]], [[3q93|3q93]]</td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">NUDT14, UGPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>

==~~About this Structure~~==

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/UDP-sugar_diphosphatase UDP-sugar diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.45 3.6.1.45] </td></tr>

[[3q91]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q91 OCA].

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q91 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q91 RCSB], [http://www.ebi.ac.uk/pdbsum/3q91 PDBsum]</td></tr>

</table>

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: UDP-sugar diphosphatase]]

[[Category: Arrowsmith, C H.]]

[[Category: Arrowsmith, C H]]

[[Category: Berg, S Van Der.]]

[[Category: Berg, S Van Der]]

[[Category: Berglund, H.]]

[[Category: Berglund, H]]

[[Category: Bountra, C.]]

[[Category: Bountra, C]]

[[Category: Collins, R.]]

[[Category: Collins, R]]

[[Category: Edwards, A M.]]

[[Category: Edwards, A M]]

[[Category: Ekblad, T.]]

[[Category: Ekblad, T]]

[[Category: Flodin, S.]]

[[Category: Flodin, S]]

[[Category: Flores, A.]]

[[Category: Flores, A]]

[[Category: Graslund, S.]]

[[Category: Graslund, S]]

[[Category: Hammarstrom, M.]]

[[Category: Hammarstrom, M]]

[[Category: Johansson, I.]]

[[Category: Johansson, I]]

[[Category: Karlberg, T.]]

[[Category: Karlberg, T]]

[[Category: Kol, S.]]

[[Category: Kol, S]]

[[Category: Kotenyova, T.]]

[[Category: Kotenyova, T]]

[[Category: Kouznetsova, E.]]

[[Category: Kouznetsova, E]]

[[Category: Moche, M.]]

[[Category: Moche, M]]

[[Category: Nordlund, P.]]

[[Category: Nordlund, P]]

[[Category: Nyman, T.]]

[[Category: Nyman, T]]

[[Category: Persson, C.]]

[[Category: Persson, C]]

[[Category: ~~SGC,~~ Structural ~~Genomics Consortium.~~]]

[[Category: Structural genomic]]

[[Category: Schuler, H.]]

[[Category: Schuler, H]]

[[Category: Schutz, P.]]

[[Category: Schutz, P]]

[[Category: Siponen, M I.]]

[[Category: Siponen, M I]]

[[Category: Thorsell, A G.]]

[[Category: Thorsell, A G]]

[[Category: Tresaugues, L.]]

[[Category: Tresaugues, L]]

[[Category: Wahlberg, E.]]

[[Category: Wahlberg, E]]

[[Category: Weigelt, J.]]

[[Category: Weigelt, J]]

[[Category: Welin, M.]]

[[Category: Welin, M]]

[[Category: Hydrolase]]

[[Category: Magnesium binding]]

Line 43:

Line 46:

[[Category: Nudix]]

[[Category: Sgc]]

~~[[Category: Structural genomic]]~~

~~[[Category: Structural genomics consortium]]~~

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-{{STRUCTURE_3q91|  PDB=3q91  |  SCENE=  }}
+==Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)==
-===Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)===
+<StructureSection load='3q91' size='340' side='right' caption='[[3q91]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[3q91]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q91 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q91 FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/NUD14_HUMAN NUD14_HUMAN]] Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose.
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q90|3q90]], [[3q93|3q93]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NUDT14, UGPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-==About this Structure==
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-sugar_diphosphatase UDP-sugar diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.45 3.6.1.45] </span></td></tr>
-[[3q91]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q91 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q91 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q91 RCSB], [http://www.ebi.ac.uk/pdbsum/3q91 PDBsum]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
 [[Category: UDP-sugar diphosphatase]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Arrowsmith, C H]]
-[[Category: Berg, S Van Der.]]
+[[Category: Berg, S Van Der]]
-[[Category: Berglund, H.]]
+[[Category: Berglund, H]]
-[[Category: Bountra, C.]]
+[[Category: Bountra, C]]
-[[Category: Collins, R.]]
+[[Category: Collins, R]]
-[[Category: Edwards, A M.]]
+[[Category: Edwards, A M]]
-[[Category: Ekblad, T.]]
+[[Category: Ekblad, T]]
-[[Category: Flodin, S.]]
+[[Category: Flodin, S]]
-[[Category: Flores, A.]]
+[[Category: Flores, A]]
-[[Category: Graslund, S.]]
+[[Category: Graslund, S]]
-[[Category: Hammarstrom, M.]]
+[[Category: Hammarstrom, M]]
-[[Category: Johansson, I.]]
+[[Category: Johansson, I]]
-[[Category: Karlberg, T.]]
+[[Category: Karlberg, T]]
-[[Category: Kol, S.]]
+[[Category: Kol, S]]
-[[Category: Kotenyova, T.]]
+[[Category: Kotenyova, T]]
-[[Category: Kouznetsova, E.]]
+[[Category: Kouznetsova, E]]
-[[Category: Moche, M.]]
+[[Category: Moche, M]]
-[[Category: Nordlund, P.]]
+[[Category: Nordlund, P]]
-[[Category: Nyman, T.]]
+[[Category: Nyman, T]]
-[[Category: Persson, C.]]
+[[Category: Persson, C]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Structural genomic]]
-[[Category: Schuler, H.]]
+[[Category: Schuler, H]]
-[[Category: Schutz, P.]]
+[[Category: Schutz, P]]
-[[Category: Siponen, M I.]]
+[[Category: Siponen, M I]]
-[[Category: Thorsell, A G.]]
+[[Category: Thorsell, A G]]
-[[Category: Tresaugues, L.]]
+[[Category: Tresaugues, L]]
-[[Category: Wahlberg, E.]]
+[[Category: Wahlberg, E]]
-[[Category: Weigelt, J.]]
+[[Category: Weigelt, J]]
-[[Category: Welin, M.]]
+[[Category: Welin, M]]
 [[Category: Hydrolase]]
 [[Category: Magnesium binding]]
@@ Line 43: / Line 46: @@
 [[Category: Nudix]]
 [[Category: Sgc]]
-[[Category: Structural genomic]]
-[[Category: Structural genomics consortium]]