1r50: Difference between revisions

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[[Image:1r50.jpg|left|200px]]<br /><applet load="1r50" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1r50.jpg|left|200px]]
caption="1r50, resolution 1.45&Aring;" />
 
'''Bacillus subtilis lipase A with covalently bound Sc-IPG-phosphonate-inhibitor'''<br />
{{Structure
|PDB= 1r50 |SIZE=350|CAPTION= <scene name='initialview01'>1r50</scene>, resolution 1.45&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SIL:[(4S)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YL]METHYL HYDROGEN HEX-5-ENYLPHOSPHONATE'>SIL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3]
|GENE= lipA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])
}}
 
'''Bacillus subtilis lipase A with covalently bound Sc-IPG-phosphonate-inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1R50 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] with <scene name='pdbligand=SIL:'>SIL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R50 OCA].  
1R50 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R50 OCA].  


==Reference==
==Reference==
Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection., Droge MJ, Boersma YL, van Pouderoyen G, Vrenken TE, Ruggeberg CJ, Reetz MT, Dijkstra BW, Quax WJ, Chembiochem. 2006 Jan;7(1):149-57. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16342303 16342303]
Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection., Droge MJ, Boersma YL, van Pouderoyen G, Vrenken TE, Ruggeberg CJ, Reetz MT, Dijkstra BW, Quax WJ, Chembiochem. 2006 Jan;7(1):149-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16342303 16342303]
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: phosphonate inhibitor]]
[[Category: phosphonate inhibitor]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:47:08 2008''
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