3wgu: Difference between revisions

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~~{{STRUCTURE_3wgu| PDB=3wgu | SCENE= }}~~

==Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state without oligomycin==

===Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state without oligomycin===

== Structural highlights ==

==~~Function~~==

<table><tr><td colspan='2'>[[3wgu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WGU OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WGU FirstGlance].

[[~~http://www.uniprot.org/uniprot/AT1B1_PIG AT1B1_PIG~~]] ~~This is the non-catalytic component of the active enzyme~~, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[2zxe|2zxe]], [[2zbd|2zbd]], [[3wgv|3wgv]]</td></tr>

==~~About this Structure~~==

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Sodium/potassium-exchanging_ATPase Sodium/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.9 3.6.3.9] </td></tr>

[[3wgu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WGU OCA].

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wgu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wgu RCSB], [http://www.ebi.ac.uk/pdbsum/3wgu PDBsum]</td></tr>

</table>

__TOC__

</StructureSection>

[[Category: Sodium/potassium-exchanging ATPase]]

[[Category: Sus scrofa]]

[[Category: Cornelius, F.]]

[[Category: Cornelius, F]]

[[Category: Kanai, R.]]

[[Category: Kanai, R]]

[[Category: Ogawa, H.]]

[[Category: Ogawa, H]]

[[Category: Toyoshima, C.]]

[[Category: Toyoshima, C]]

[[Category: Vilsen, B.]]

[[Category: Vilsen, B]]

[[Category: Atp-binding]]

[[Category: Atpase]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_3wgu|  PDB=3wgu  |  SCENE=  }}
+==Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state without oligomycin==
-===Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state without oligomycin===
+<StructureSection load='3wgu' size='340' side='right' caption='[[3wgu]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[3wgu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WGU FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/AT1B1_PIG AT1B1_PIG]] This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zxe|2zxe]], [[2zbd|2zbd]], [[3wgv|3wgv]]</td></tr>
-==About this Structure==
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sodium/potassium-exchanging_ATPase Sodium/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.9 3.6.3.9] </span></td></tr>
-[[3wgu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WGU OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wgu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wgu RCSB], [http://www.ebi.ac.uk/pdbsum/3wgu PDBsum]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
 [[Category: Sodium/potassium-exchanging ATPase]]
 [[Category: Sus scrofa]]
-[[Category: Cornelius, F.]]
+[[Category: Cornelius, F]]
-[[Category: Kanai, R.]]
+[[Category: Kanai, R]]
-[[Category: Ogawa, H.]]
+[[Category: Ogawa, H]]
-[[Category: Toyoshima, C.]]
+[[Category: Toyoshima, C]]
-[[Category: Vilsen, B.]]
+[[Category: Vilsen, B]]
 [[Category: Atp-binding]]
 [[Category: Atpase]]