1rf7: Difference between revisions

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[[Image:1rf7.jpg|left|200px]]<br /><applet load="1rf7" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1rf7.jpg|left|200px]]
caption="1rf7, resolution 1.8&Aring;" />
 
'''STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDROFOLATE'''<br />
{{Structure
|PDB= 1rf7 |SIZE=350|CAPTION= <scene name='initialview01'>1rf7</scene>, resolution 1.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=DHF:DIHYDROFOLIC ACID'>DHF</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3]
|GENE=
}}
 
'''STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDROFOLATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1RF7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=DHF:'>DHF</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RF7 OCA].  
1RF7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RF7 OCA].  


==Reference==
==Reference==
Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence., Sawaya MR, Kraut J, Biochemistry. 1997 Jan 21;36(3):586-603. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9012674 9012674]
Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence., Sawaya MR, Kraut J, Biochemistry. 1997 Jan 21;36(3):586-603. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9012674 9012674]
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: trimethoprim resistance]]
[[Category: trimethoprim resistance]]


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Retrieved from "https://proteopedia.org/1rf7"