4bim: Difference between revisions

Line 1:

~~{{STRUCTURE_4bim| PDB=4bim | SCENE= }}~~

==CATALASE 3 FROM NEUROSPORA CRASSA IN TETRAGONAL FORM EXPOSES A MODIFIED TETRAMERIC ORGANIZATION==

===CATALASE 3 FROM NEUROSPORA CRASSA IN TETRAGONAL FORM EXPOSES A MODIFIED TETRAMERIC ORGANIZATION===

~~{{ABSTRACT_PUBMED_23832201}}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4bim]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Neurospora_crassa Neurospora crassa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BIM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BIM FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bim OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bim RCSB], [http://www.ebi.ac.uk/pdbsum/4bim PDBsum]</span></td></tr>

</table>

== Publication Abstract from PubMed ==

Polymorphism is frequently observed from different crystallization conditions. In proteins, the effect on conformational variability is poorly documented, with only a few reported examples. Here, three polymorphic crystal structures determined for a large-subunit catalase, CAT-3 from Neurospora crassa, are reported. Two of them belonged to new space groups, P1 and P43212, and a third structure belonged to the same space group, P212121, as the previously deposited 2.3 A resolution structure (PDB entry 3ej6), but had a higher resolution (1.95 A). Comparisons between these polymorphic structures highlight the conformational stability of tetrameric CAT-3 and reveal a distortion in the tetrameric structure that has not previously been described.

~~==Function==~~

Conformational stability and crystal packing: polymorphism in Neurospora crassa CAT-3.,Zarate-Romero A, Stojanoff V, Rojas-Trejo SP, Hansberg W, Rudino-Pinera E Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jul 1;69(Pt 7):753-8. doi:, 10.1107/S1744309113013468. Epub 2013 Jun 27. PMID:23832201<ref>PMID:23832201</ref>

~~[[http~~:~~//www~~.~~uniprot~~.~~org/uniprot/CAT3_NEUCR CAT3_NEUCR]] Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide~~ (~~By similarity~~).

~~==About this Structure==~~

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

~~[[4bim]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Neurospora_crassa Neurospora crassa]~~. ~~Full crystallographic information is available from [http:/~~/~~oca.weizmann.ac.il/oca-bin/ocashort?id=4BIM OCA].~~

</div>

==~~Reference~~==

==See Also==

~~<ref group~~=~~"xtra">PMID:023832201</ref>~~<references ~~group="xtra"~~/><~~references~~/>

*[[Catalase|Catalase]]

== References ==

__TOC__

</StructureSection>

[[Category: Catalase]]

[[Category: Neurospora crassa]]

[[Category: Rudino-Pinera, E.]]

[[Category: Rudino-Pinera, E]]

[[Category: Zarate-Romero, A.]]

[[Category: Zarate-Romero, A]]

[[Category: Large subunit catalase]]

[[Category: Modified tetramer]]

[[Category: Oxidoreductase]]

[[Category: Peroxidase]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4bim|  PDB=4bim  |  SCENE=  }}
+==CATALASE 3 FROM NEUROSPORA CRASSA IN TETRAGONAL FORM EXPOSES A MODIFIED TETRAMERIC ORGANIZATION==
-===CATALASE 3 FROM NEUROSPORA CRASSA IN TETRAGONAL FORM EXPOSES A MODIFIED TETRAMERIC ORGANIZATION===
+<StructureSection load='4bim' size='340' side='right' caption='[[4bim]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
-{{ABSTRACT_PUBMED_23832201}}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4bim]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Neurospora_crassa Neurospora crassa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BIM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BIM FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bim OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bim RCSB], [http://www.ebi.ac.uk/pdbsum/4bim PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Polymorphism is frequently observed from different crystallization conditions. In proteins, the effect on conformational variability is poorly documented, with only a few reported examples. Here, three polymorphic crystal structures determined for a large-subunit catalase, CAT-3 from Neurospora crassa, are reported. Two of them belonged to new space groups, P1 and P43212, and a third structure belonged to the same space group, P212121, as the previously deposited 2.3 A resolution structure (PDB entry 3ej6), but had a higher resolution (1.95 A). Comparisons between these polymorphic structures highlight the conformational stability of tetrameric CAT-3 and reveal a distortion in the tetrameric structure that has not previously been described.
-==Function==
+Conformational stability and crystal packing: polymorphism in Neurospora crassa CAT-3.,Zarate-Romero A, Stojanoff V, Rojas-Trejo SP, Hansberg W, Rudino-Pinera E Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jul 1;69(Pt 7):753-8. doi:, 10.1107/S1744309113013468. Epub 2013 Jun 27. PMID:23832201<ref>PMID:23832201</ref>
-[[http://www.uniprot.org/uniprot/CAT3_NEUCR CAT3_NEUCR]] Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide (By similarity).
-==About this Structure==
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[4bim]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Neurospora_crassa Neurospora crassa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BIM OCA].
+</div>
-==Reference==
+==See Also==
-<ref group="xtra">PMID:023832201</ref><references group="xtra"/><references/>
+*[[Catalase|Catalase]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Catalase]]
 [[Category: Neurospora crassa]]
-[[Category: Rudino-Pinera, E.]]
+[[Category: Rudino-Pinera, E]]
-[[Category: Zarate-Romero, A.]]
+[[Category: Zarate-Romero, A]]
 [[Category: Large subunit catalase]]
 [[Category: Modified tetramer]]
 [[Category: Oxidoreductase]]
 [[Category: Peroxidase]]