1rnj: Difference between revisions

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[[Image:1rnj.gif|left|200px]]<br /><applet load="1rnj" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1rnj.gif|left|200px]]
caption="1rnj, resolution 1.70&Aring;" />
 
'''Crystal structure of inactive mutant dUTPase complexed with substrate analogue imido-dUTP'''<br />
{{Structure
|PDB= 1rnj |SIZE=350|CAPTION= <scene name='initialview01'>1rnj</scene>, resolution 1.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=DUP:2'-DEOXYURIDINE+5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE'>DUP</scene> and <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23]
|GENE= DUT, DNAS, SOF, B3640 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Crystal structure of inactive mutant dUTPase complexed with substrate analogue imido-dUTP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1RNJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=DUP:'>DUP</scene> and <scene name='pdbligand=TRS:'>TRS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNJ OCA].  
1RNJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNJ OCA].  


==Reference==
==Reference==
Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase., Barabas O, Pongracz V, Kovari J, Wilmanns M, Vertessy BG, J Biol Chem. 2004 Oct 8;279(41):42907-15. Epub 2004 Jun 17. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15208312 15208312]
Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase., Barabas O, Pongracz V, Kovari J, Wilmanns M, Vertessy BG, J Biol Chem. 2004 Oct 8;279(41):42907-15. Epub 2004 Jun 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15208312 15208312]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: jelly roll]]
[[Category: jelly roll]]


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