1roz: Difference between revisions

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[[Image:1roz.gif|left|200px]]~~<br /><applet load~~="1roz~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1roz.gif|left|200px]]

~~caption="~~1roz, resolution 2.21Å" />

'''Deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form'''~~<br />~~

{{Structure

|PDB= 1roz |SIZE=350|CAPTION= <scene name='initialview01'>1roz</scene>, resolution 2.21Å

|SITE=

|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Deoxyhypusine_synthase Deoxyhypusine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.46 2.5.1.46]

|GENE= DHPS, DS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])

}}

'''Deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form'''

==Overview==

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==About this Structure==

1ROZ is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] ~~with <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia~~.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Deoxyhypusine_synthase Deoxyhypusine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.46 2.5.1.46] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROZ OCA].

1ROZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROZ OCA].

==Reference==

A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme.NAD.inhibitor ternary complex., Umland TC, Wolff EC, Park MH, Davies DR, J Biol Chem. 2004 Jul 2;279(27):28697-705. Epub 2004 Apr 20. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~15100216 15100216]

A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme.NAD.inhibitor ternary complex., Umland TC, Wolff EC, Park MH, Davies DR, J Biol Chem. 2004 Jul 2;279(27):28697-705. Epub 2004 Apr 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15100216 15100216]

[[Category: Deoxyhypusine synthase]]

[[Category: Homo sapiens]]

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[[Category: spermidine]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 14~~:53:03 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:54:22 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1roz.gif|left|200px]]<br /><applet load="1roz" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1roz.gif|left|200px]]
-caption="1roz, resolution 2.21&Aring;" />
-'''Deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form'''<br />
+ {{Structure
+|PDB= 1roz |SIZE=350|CAPTION= <scene name='initialview01'>1roz</scene>, resolution 2.21&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Deoxyhypusine_synthase Deoxyhypusine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.46 2.5.1.46]
+|GENE= DHPS, DS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''Deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-ROZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Deoxyhypusine_synthase Deoxyhypusine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.46 2.5.1.46] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROZ OCA].
+ROZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROZ OCA].
 ==Reference==
-A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme.NAD.inhibitor ternary complex., Umland TC, Wolff EC, Park MH, Davies DR, J Biol Chem. 2004 Jul 2;279(27):28697-705. Epub 2004 Apr 20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15100216 15100216]
+A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme.NAD.inhibitor ternary complex., Umland TC, Wolff EC, Park MH, Davies DR, J Biol Chem. 2004 Jul 2;279(27):28697-705. Epub 2004 Apr 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15100216 15100216]
 [[Category: Deoxyhypusine synthase]]
 [[Category: Homo sapiens]]
@@ Line 28: / Line 37: @@
 [[Category: spermidine]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:53:03 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:54:22 2008''