1rpn: Difference between revisions

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[[Image:1rpn.jpg|left|200px]]<br /><applet load="1rpn" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1rpn.jpg|left|200px]]
caption="1rpn, resolution 2.15&Aring;" />
 
'''Crystal Structure of GDP-D-mannose 4,6-dehydratase in complexes with GDP and NADPH'''<br />
{{Structure
|PDB= 1rpn |SIZE=350|CAPTION= <scene name='initialview01'>1rpn</scene>, resolution 2.15&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene> and <scene name='pdbligand=GDP:GUANOSINE-5'-DIPHOSPHATE'>GDP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/GDP-mannose_4,6-dehydratase GDP-mannose 4,6-dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.47 4.2.1.47]
|GENE= GCA, PA5453 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])
}}
 
'''Crystal Structure of GDP-D-mannose 4,6-dehydratase in complexes with GDP and NADPH'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1RPN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] with <scene name='pdbligand=NDP:'>NDP</scene> and <scene name='pdbligand=GDP:'>GDP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/GDP-mannose_4,6-dehydratase GDP-mannose 4,6-dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.47 4.2.1.47] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RPN OCA].  
1RPN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RPN OCA].  


==Reference==
==Reference==
Crystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathway., Webb NA, Mulichak AM, Lam JS, Rocchetta HL, Garavito RM, Protein Sci. 2004 Feb;13(2):529-39. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14739333 14739333]
Crystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathway., Webb NA, Mulichak AM, Lam JS, Rocchetta HL, Garavito RM, Protein Sci. 2004 Feb;13(2):529-39. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14739333 14739333]
[[Category: GDP-mannose 4,6-dehydratase]]
[[Category: GDP-mannose 4,6-dehydratase]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: short-chain dehydrogenase/reductase]]
[[Category: short-chain dehydrogenase/reductase]]


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