4gfv: Difference between revisions

Line 1:

~~{{STRUCTURE_4gfv~~| ~~PDB~~=4gfv | ~~SCENE~~= }}

==PTPN18 in complex with HER2-pY1196 phosphor-peptides==

===PTPN18 ~~in complex~~ with ~~HER2~~-~~pY1196 phosphor~~-~~peptides~~===

== Structural highlights ==

<table><tr><td colspan='2'>[[4gfv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFV OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GFV FirstGlance].

</td></tr><tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4gfu|4gfu]], [[4gfw|4gfw]]</td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">PTPN18, BDP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gfv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gfv RCSB], [http://www.ebi.ac.uk/pdbsum/4gfv PDBsum]</td></tr>

</table>

==~~Function~~==

==See Also==

[[~~http://www.uniprot.org/uniprot/PTN18_HUMAN PTN18_HUMAN~~]] ~~Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.~~

*[[Tyrosine phosphatase|Tyrosine phosphatase]]

__TOC__

~~==About this Structure==~~

</StructureSection>

~~[[4gfv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin~~/~~ocashort?id=4GFV OCA].~~

[[Category: Homo sapiens]]

[[Category: Protein-tyrosine-phosphatase]]

[[Category: Du, Y J.]]

[[Category: Du, Y J]]

[[Category: Sun, J P.]]

[[Category: Sun, J P]]

[[Category: Wang, H M.]]

[[Category: Wang, H M]]

[[Category: Yang, D X.]]

[[Category: Yang, D X]]

[[Category: Yang, F.]]

[[Category: Yang, F]]

[[Category: Yu, X.]]

[[Category: Yu, X]]

[[Category: Zhang, Y.]]

[[Category: Zhang, Y]]

[[Category: Hydrolase]]

[[Category: Hydrolase-peptide complex]]

[[Category: Phosphatase]]

[[Category: Tyrosine phosphorylation]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4gfv|  PDB=4gfv  |  SCENE=  }}
+==PTPN18 in complex with HER2-pY1196 phosphor-peptides==
-===PTPN18 in complex with HER2-pY1196 phosphor-peptides===
+<StructureSection load='4gfv' size='340' side='right' caption='[[4gfv]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4gfv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GFV FirstGlance]. <br>
+</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gfu|4gfu]], [[4gfw|4gfw]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPN18, BDP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gfv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gfv RCSB], [http://www.ebi.ac.uk/pdbsum/4gfv PDBsum]</span></td></tr>
+</table>
-==Function==
+==See Also==
-[[http://www.uniprot.org/uniprot/PTN18_HUMAN PTN18_HUMAN]] Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.
+*[[Tyrosine phosphatase|Tyrosine phosphatase]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[4gfv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFV OCA].
 [[Category: Homo sapiens]]
 [[Category: Protein-tyrosine-phosphatase]]
-[[Category: Du, Y J.]]
+[[Category: Du, Y J]]
-[[Category: Sun, J P.]]
+[[Category: Sun, J P]]
-[[Category: Wang, H M.]]
+[[Category: Wang, H M]]
-[[Category: Yang, D X.]]
+[[Category: Yang, D X]]
-[[Category: Yang, F.]]
+[[Category: Yang, F]]
-[[Category: Yu, X.]]
+[[Category: Yu, X]]
-[[Category: Zhang, Y.]]
+[[Category: Zhang, Y]]
 [[Category: Hydrolase]]
 [[Category: Hydrolase-peptide complex]]
 [[Category: Phosphatase]]
 [[Category: Tyrosine phosphorylation]]