4el6: Difference between revisions
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==Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs== | |||
<StructureSection load='4el6' size='340' side='right' caption='[[4el6]], [[Resolution|resolution]] 1.71Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4el6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EL6 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4el6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4el6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4el6 RCSB], [http://www.ebi.ac.uk/pdbsum/4el6 PDBsum]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1) triggers the release of large amounts of interleukin-4 from human blood basophils, thus presumably playing an immunomodulatory role during schistosome infection. IPSE/alpha-1 was crystallized and a native X-ray data set was collected to 1.66 A resolution from a single crystal at 100 K using synchrotron radiation. The crystal belonged to space group P6(1) or P6(5), with one molecule per asymmetric unit. | |||
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1).,Mayerhofer H, Schramm G, Hatzopoulos GN, Mueller-Dieckmann C, Haas H, Mueller-Dieckmann J Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jun 1;65(Pt 6):594-6. doi:, 10.1107/S1744309109015899. Epub 2009 May 22. PMID:19478439<ref>PMID:19478439</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Schistosoma mansoni]] | [[Category: Schistosoma mansoni]] | ||
[[Category: Bade, S | [[Category: Bade, S]] | ||
[[Category: Barths, D | [[Category: Barths, D]] | ||
[[Category: Blindow, S | [[Category: Blindow, S]] | ||
[[Category: Frey, A | [[Category: Frey, A]] | ||
[[Category: Haas, H | [[Category: Haas, H]] | ||
[[Category: Madl, T | [[Category: Madl, T]] | ||
[[Category: Mayerhofer, H | [[Category: Mayerhofer, H]] | ||
[[Category: Meyer, H | [[Category: Meyer, H]] | ||
[[Category: Mueller-Dieckmann, J | [[Category: Mueller-Dieckmann, J]] | ||
[[Category: Sattler, M | [[Category: Sattler, M]] | ||
[[Category: Schramm, G | [[Category: Schramm, G]] | ||
[[Category: Tripsianes, K | [[Category: Tripsianes, K]] | ||
[[Category: Beta/gamma-crystallin superfamily]] | [[Category: Beta/gamma-crystallin superfamily]] | ||
[[Category: Ige]] | [[Category: Ige]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
[[Category: Triggers il4 release]] | [[Category: Triggers il4 release]] | ||
