1s1s: Difference between revisions

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[[Image:1s1s.gif|left|200px]]~~<br /><applet load~~="1s1s~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1s1s.gif|left|200px]]

~~caption="~~1s1s, resolution 2.10Å" />

'''Crystal Structure of ZipA in complex with indoloquinolizin 10b'''~~<br />~~

{{Structure

|PDB= 1s1s |SIZE=350|CAPTION= <scene name='initialview01'>1s1s</scene>, resolution 2.10Å

|SITE=

|LIGAND= <scene name='pdbligand=WAC:N-{3-[(7AR,12AS,12BS)-7-OXO-1,3,4,6,7,7A,12A,12B-OCTAHYDROINDOLO[2,3-A]QUINOLIZIN-12(2H)-YL]PROPYL}PROPANE-2-SULFONAMIDE'>WAC</scene>

|ACTIVITY=

|GENE= ZIPA, B2412 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])

}}

'''Crystal Structure of ZipA in complex with indoloquinolizin 10b'''

==Overview==

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==About this Structure==

1S1S is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli~~] with <scene name='pdbligand=WAC:'>WAC</scene> as [http://en.wikipedia.org/wiki/ligand ligand~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S1S OCA].

1S1S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S1S OCA].

==Reference==

Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction., Jennings LD, Foreman KW, Rush TS 3rd, Tsao DH, Mosyak L, Li Y, Sukhdeo MN, Ding W, Dushin EG, Kenny CH, Moghazeh SL, Petersen PJ, Ruzin AV, Tuckman M, Sutherland AG, Bioorg Med Chem Lett. 2004 Mar 22;14(6):1427-31. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~15006376 15006376]

Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction., Jennings LD, Foreman KW, Rush TS 3rd, Tsao DH, Mosyak L, Li Y, Sukhdeo MN, Ding W, Dushin EG, Kenny CH, Moghazeh SL, Petersen PJ, Ruzin AV, Tuckman M, Sutherland AG, Bioorg Med Chem Lett. 2004 Mar 22;14(6):1427-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15006376 15006376]

[[Category: Escherichia coli]]

[[Category: Single protein]]

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[[Category: cell cycle]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:59:17 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1s1s.gif|left|200px]]<br /><applet load="1s1s" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1s1s.gif|left|200px]]
-caption="1s1s, resolution 2.10&Aring;" />
-'''Crystal Structure of ZipA in complex with indoloquinolizin 10b'''<br />
+ {{Structure
+|PDB= 1s1s |SIZE=350|CAPTION= <scene name='initialview01'>1s1s</scene>, resolution 2.10&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=WAC:N-{3-[(7AR,12AS,12BS)-7-OXO-1,3,4,6,7,7A,12A,12B-OCTAHYDROINDOLO[2,3-A]QUINOLIZIN-12(2H)-YL]PROPYL}PROPANE-2-SULFONAMIDE'>WAC</scene>
+|ACTIVITY=
+|GENE= ZIPA, B2412 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+}}
+'''Crystal Structure of ZipA in complex with indoloquinolizin 10b'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-S1S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=WAC:'>WAC</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S1S OCA].
+S1S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S1S OCA].
 ==Reference==
-Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction., Jennings LD, Foreman KW, Rush TS 3rd, Tsao DH, Mosyak L, Li Y, Sukhdeo MN, Ding W, Dushin EG, Kenny CH, Moghazeh SL, Petersen PJ, Ruzin AV, Tuckman M, Sutherland AG, Bioorg Med Chem Lett. 2004 Mar 22;14(6):1427-31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15006376 15006376]
+Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction., Jennings LD, Foreman KW, Rush TS 3rd, Tsao DH, Mosyak L, Li Y, Sukhdeo MN, Ding W, Dushin EG, Kenny CH, Moghazeh SL, Petersen PJ, Ruzin AV, Tuckman M, Sutherland AG, Bioorg Med Chem Lett. 2004 Mar 22;14(6):1427-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15006376 15006376]
 [[Category: Escherichia coli]]
 [[Category: Single protein]]
@@ Line 31: / Line 40: @@
 [[Category: cell cycle]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:56:59 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:59:17 2008''