4hpw: Difference between revisions

Line 1:

~~{{STRUCTURE_4hpw| PDB=4hpw | SCENE= }}~~

==Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine==

===Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine===

== Structural highlights ==

==~~Function~~==

<table><tr><td colspan='2'>[[4hpw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPW OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HPW FirstGlance].

[[~~http://www.uniprot.org/uniprot/SYY_METJA SYY_METJA~~]] ~~Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)~~.~~<ref~~>~~PMID:10585437</ref>~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=3YM:3-METHOXY-L-TYROSINE'>3YM</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4hk4|4hk4]]</td></tr>

==~~About this Structure~~==

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">tyrS, MJ0389 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 Methanocaldococcus jannaschii DSM 2661])</td></tr>

[[4hpw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPW OCA].

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Tyrosine--tRNA_ligase Tyrosine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.1 6.1.1.1] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hpw RCSB], [http://www.ebi.ac.uk/pdbsum/4hpw PDBsum]</td></tr>

==~~Reference~~==

</table>

<~~references group~~="~~xtra~~"/><~~references~~/>

__TOC__

</StructureSection>

[[Category: Methanocaldococcus jannaschii dsm 2661]]

[[Category: Tyrosine--tRNA ligase]]

[[Category: Dong, J.]]

[[Category: Dong, J]]

[[Category: Gao, F.]]

[[Category: Gao, F]]

[[Category: Gong, W.]]

[[Category: Gong, W]]

[[Category: Li, H.]]

[[Category: Li, H]]

[[Category: Li, J.]]

[[Category: Li, J]]

[[Category: Lu, Y.]]

[[Category: Lu, Y]]

[[Category: Mukherjee, A.]]

[[Category: Mukherjee, A]]

[[Category: Nilges, M.]]

[[Category: Nilges, M]]

[[Category: Ouyang, H.]]

[[Category: Ouyang, H]]

[[Category: Wang, J.]]

[[Category: Wang, J]]

[[Category: Xiaoxuan, L.]]

[[Category: Xiaoxuan, L]]

[[Category: Yang, Y.]]

[[Category: Yang, Y]]

[[Category: Zhou, Q.]]

[[Category: Zhou, Q]]

[[Category: 3-o-methyl tyrosine incorporation]]

[[Category: Ligase]]

[[Category: Trna]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4hpw|  PDB=4hpw  |  SCENE=  }}
+==Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine==
-===Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine===
+<StructureSection load='4hpw' size='340' side='right' caption='[[4hpw]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[4hpw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HPW FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/SYY_METJA SYY_METJA]] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<ref>PMID:10585437</ref>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3YM:3-METHOXY-L-TYROSINE'>3YM</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hk4|4hk4]]</td></tr>
-==About this Structure==
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tyrS, MJ0389 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 Methanocaldococcus jannaschii DSM 2661])</td></tr>
-[[4hpw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPW OCA].
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tyrosine--tRNA_ligase Tyrosine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.1 6.1.1.1] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hpw RCSB], [http://www.ebi.ac.uk/pdbsum/4hpw PDBsum]</span></td></tr>
-==Reference==
+</table>
-<references group="xtra"/><references/>
+__TOC__
+</StructureSection>
 [[Category: Methanocaldococcus jannaschii dsm 2661]]
 [[Category: Tyrosine--tRNA ligase]]
-[[Category: Dong, J.]]
+[[Category: Dong, J]]
-[[Category: Gao, F.]]
+[[Category: Gao, F]]
-[[Category: Gong, W.]]
+[[Category: Gong, W]]
-[[Category: Li, H.]]
+[[Category: Li, H]]
-[[Category: Li, J.]]
+[[Category: Li, J]]
-[[Category: Lu, Y.]]
+[[Category: Lu, Y]]
-[[Category: Mukherjee, A.]]
+[[Category: Mukherjee, A]]
-[[Category: Nilges, M.]]
+[[Category: Nilges, M]]
-[[Category: Ouyang, H.]]
+[[Category: Ouyang, H]]
-[[Category: Wang, J.]]
+[[Category: Wang, J]]
-[[Category: Xiaoxuan, L.]]
+[[Category: Xiaoxuan, L]]
-[[Category: Yang, Y.]]
+[[Category: Yang, Y]]
-[[Category: Zhou, Q.]]
+[[Category: Zhou, Q]]
 [[Category: 3-o-methyl tyrosine incorporation]]
 [[Category: Ligase]]
 [[Category: Trna]]