4i18: Difference between revisions

Line 1:

~~{{STRUCTURE_4i18| PDB=4i18 | SCENE= }}~~

==Crystal structure of human prolactin receptor complexed with Fab fragment==

===Crystal structure of human prolactin receptor complexed with Fab fragment===

== Structural highlights ==

<table><tr><td colspan='2'>[[4i18]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I18 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I18 FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">PRLR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i18 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i18 RCSB], [http://www.ebi.ac.uk/pdbsum/4i18 PDBsum]</td></tr>

</table>

==~~Function~~==

==See Also==

[[~~http://www.uniprot.org/uniprot/PRLR_HUMAN PRLR_HUMAN~~]] ~~This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.<ref>PMID:12580759~~</~~ref~~>

*[[Antibody|Antibody]]

__TOC__

~~==About this Structure==~~

</StructureSection>

[[~~4i18~~]] ~~is a 6 chain structure. Full crystallographic information is available from~~ [~~http~~:~~//oca.weizmann.ac.il/oca-bin/ocashort?id=4I18 OCA~~].

[[Category: Human]]

[[Category: Lk3 transgenic mice]]

~~==Reference==~~

[[Category: Duguid, E M]]

~~<references group="xtra"/><references/>~~

[[Category: Kouadio, J L]]

[[Category: Duguid, E M.]]

[[Category: Mukherjee, S]]

[[Category: Kouadio, J L.]]

[[Category: Mukherjee, S.]]

[[Category: Cytokine]]

[[Category: Immunoglobulin fold]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4i18|  PDB=4i18  |  SCENE=  }}
+==Crystal structure of human prolactin receptor complexed with Fab fragment==
-===Crystal structure of human prolactin receptor complexed with Fab fragment===
+<StructureSection load='4i18' size='340' side='right' caption='[[4i18]], [[Resolution|resolution]] 3.24&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4i18]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I18 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I18 FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRLR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i18 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i18 RCSB], [http://www.ebi.ac.uk/pdbsum/4i18 PDBsum]</span></td></tr>
+</table>
-==Function==
+==See Also==
-[[http://www.uniprot.org/uniprot/PRLR_HUMAN PRLR_HUMAN]] This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.<ref>PMID:12580759</ref>
+*[[Antibody|Antibody]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[4i18]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I18 OCA].
+[[Category: Human]]
+[[Category: Lk3 transgenic mice]]
-==Reference==
+[[Category: Duguid, E M]]
-<references group="xtra"/><references/>
+[[Category: Kouadio, J L]]
-[[Category: Duguid, E M.]]
+[[Category: Mukherjee, S]]
-[[Category: Kouadio, J L.]]
-[[Category: Mukherjee, S.]]
 [[Category: Cytokine]]
 [[Category: Immunoglobulin fold]]