1s78: Difference between revisions

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[[Image:1s78.jpg|left|200px]]<br /><applet load="1s78" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1s78.jpg|left|200px]]
caption="1s78, resolution 3.25&Aring;" />
 
'''Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex'''<br />
{{Structure
|PDB= 1s78 |SIZE=350|CAPTION= <scene name='initialview01'>1s78</scene>, resolution 3.25&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE= ERBB2, HER2, NGL, NEU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1S78 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=NAG:'>NAG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S78 OCA].  
1S78 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S78 OCA].  


==Reference==
==Reference==
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex., Franklin MC, Carey KD, Vajdos FF, Leahy DJ, de Vos AM, Sliwkowski MX, Cancer Cell. 2004 Apr;5(4):317-28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15093539 15093539]
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex., Franklin MC, Carey KD, Vajdos FF, Leahy DJ, de Vos AM, Sliwkowski MX, Cancer Cell. 2004 Apr;5(4):317-28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15093539 15093539]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: receptor-antibody complex]]
[[Category: receptor-antibody complex]]


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