1sc3: Difference between revisions

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[[Image:1sc3.gif|left|200px]]<br /><applet load="1sc3" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1sc3.gif|left|200px]]
caption="1sc3, resolution 1.80&Aring;" />
 
'''Crystal structure of the human caspase-1 C285A mutant in complex with malonate'''<br />
{{Structure
|PDB= 1sc3 |SIZE=350|CAPTION= <scene name='initialview01'>1sc3</scene>, resolution 1.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MLI:MALONATE ION'>MLI</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Caspase-1 Caspase-1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.36 3.4.22.36]
|GENE= CASP1, IL1BC, IL1BCE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the human caspase-1 C285A mutant in complex with malonate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1SC3 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MLI:'>MLI</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Caspase-1 Caspase-1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.36 3.4.22.36] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SC3 OCA].  
1SC3 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SC3 OCA].  


==Reference==
==Reference==
Crystal structures of a ligand-free and malonate-bound human caspase-1: implications for the mechanism of substrate binding., Romanowski MJ, Scheer JM, O'Brien T, McDowell RS, Structure. 2004 Aug;12(8):1361-71. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15296730 15296730]
Crystal structures of a ligand-free and malonate-bound human caspase-1: implications for the mechanism of substrate binding., Romanowski MJ, Scheer JM, O'Brien T, McDowell RS, Structure. 2004 Aug;12(8):1361-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15296730 15296730]
[[Category: Caspase-1]]
[[Category: Caspase-1]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: malonate-bound caspase-1]]
[[Category: malonate-bound caspase-1]]


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