4mjm: Difference between revisions

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{{STRUCTURE_4mjm|  PDB=4mjm  |  SCENE=  }}
==Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Short Internal Deletion of CBS Domain from Bacillus anthracis str. Ames==
===Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Short Internal Deletion of CBS Domain from Bacillus anthracis str. Ames===
<StructureSection load='4mjm' size='340' side='right' caption='[[4mjm]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4mjm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_str._ames Bacillus anthracis str. ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MJM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tsb|3tsb]], [[3tsd|3tsd]], [[3usb|3usb]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaB, BA_0008, BAS0011, GBAA_0008 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198094 Bacillus anthracis str. Ames])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mjm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mjm RCSB], [http://www.ebi.ac.uk/pdbsum/4mjm PDBsum]</span></td></tr>
</table>


==Function==
==See Also==
[[http://www.uniprot.org/uniprot/Q81W29_BACAN Q81W29_BACAN]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
*[[Inosine monophosphate dehydrogenase|Inosine monophosphate dehydrogenase]]
 
__TOC__
==About this Structure==
</StructureSection>
[[4mjm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_str._ames Bacillus anthracis str. ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MJM OCA].
[[Category: Bacillus anthracis str. ames]]
[[Category: Bacillus anthracis str. ames]]
[[Category: IMP dehydrogenase]]
[[Category: IMP dehydrogenase]]
[[Category: Anderson, W F.]]
[[Category: Anderson, W F]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Structural genomic]]
[[Category: Gu, M.]]
[[Category: Gu, M]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak, A]]
[[Category: Kim, Y.]]
[[Category: Kim, Y]]
[[Category: Makowska-Grzyska, M.]]
[[Category: Makowska-Grzyska, M]]
[[Category: Alpha-beta fold]]
[[Category: Alpha-beta fold]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Niaid]]
[[Category: Niaid]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Structural genomic]]
[[Category: Tim barrel]]
[[Category: Tim barrel]]