1sh9: Difference between revisions

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[[Image:1sh9.gif|left|200px]]~~<br /><applet load~~="1sh9~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1sh9.gif|left|200px]]

~~caption="~~1sh9, resolution 2.50Å" />

'''Comparing the Accumulation of Active Site and Non-active Site Mutations in the HIV-1 Protease'''~~<br />~~

{{Structure

|PDB= 1sh9 |SIZE=350|CAPTION= <scene name='initialview01'>1sh9</scene>, resolution 2.50Å

|SITE=

|LIGAND= <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]

|GENE=

}}

'''Comparing the Accumulation of Active Site and Non-active Site Mutations in the HIV-1 Protease'''

==Overview==

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==About this Structure==

1SH9 is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=RIT:'>RIT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.~~php4?ecno=3.4.23.16 3.4.23.16]~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SH9 OCA].

1SH9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SH9 OCA].

==Reference==

Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease., Clemente JC, Moose RE, Hemrajani R, Whitford LR, Govindasamy L, Reutzel R, McKenna R, Agbandje-McKenna M, Goodenow MM, Dunn BM, Biochemistry. 2004 Sep 28;43(38):12141-51. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~15379553 15379553]

Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease., Clemente JC, Moose RE, Hemrajani R, Whitford LR, Govindasamy L, Reutzel R, McKenna R, Agbandje-McKenna M, Goodenow MM, Dunn BM, Biochemistry. 2004 Sep 28;43(38):12141-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15379553 15379553]

[[Category: HIV-1 retropepsin]]

[[Category: Human immunodeficiency virus 1]]

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[[Category: Reutzel, R.]]

[[Category: RIT]]

[[Category: active site ~~mutations~~]]

[[Category: active site mutation]]

[[Category: hiv-1 protease]]

[[Category: non-active site ~~mutations~~]]

[[Category: non-active site mutation]]

[[Category: ritonavir]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 15~~:01:28 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:04:52 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1sh9.gif|left|200px]]<br /><applet load="1sh9" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1sh9.gif|left|200px]]
-caption="1sh9, resolution 2.50&Aring;" />
-'''Comparing the Accumulation of Active Site and Non-active Site Mutations in the HIV-1 Protease'''<br />
+ {{Structure
+|PDB= 1sh9 |SIZE=350|CAPTION= <scene name='initialview01'>1sh9</scene>, resolution 2.50&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]
+|GENE=
+}}
+'''Comparing the Accumulation of Active Site and Non-active Site Mutations in the HIV-1 Protease'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-SH9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=RIT:'>RIT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SH9 OCA].
+SH9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SH9 OCA].
 ==Reference==
-Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease., Clemente JC, Moose RE, Hemrajani R, Whitford LR, Govindasamy L, Reutzel R, McKenna R, Agbandje-McKenna M, Goodenow MM, Dunn BM, Biochemistry. 2004 Sep 28;43(38):12141-51. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15379553 15379553]
+Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease., Clemente JC, Moose RE, Hemrajani R, Whitford LR, Govindasamy L, Reutzel R, McKenna R, Agbandje-McKenna M, Goodenow MM, Dunn BM, Biochemistry. 2004 Sep 28;43(38):12141-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15379553 15379553]
 [[Category: HIV-1 retropepsin]]
 [[Category: Human immunodeficiency virus 1]]
@@ Line 24: / Line 33: @@
 [[Category: Reutzel, R.]]
 [[Category: RIT]]
-[[Category: active site mutations]]
+[[Category: active site mutation]]
 [[Category: hiv-1 protease]]
-[[Category: non-active site mutations]]
+[[Category: non-active site mutation]]
 [[Category: ritonavir]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:01:28 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:04:52 2008''