4nf2: Difference between revisions

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~~{{STRUCTURE_4nf2| PDB=4nf2 | SCENE= }}~~

==Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline==

===Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline===

== Structural highlights ==

<table><tr><td colspan='2'>[[4nf2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_ames_"ancestor" Bacillus anthracis ames "ancestor"]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NF2 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NF2 FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CP:PHOSPHORIC+ACID+MONO(FORMAMIDE)ESTER'>CP</scene>, <scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4ep1|4ep1]]</td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">argF, BAS4036, BA_4351, GBAA_4351 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=261594 Bacillus anthracis Ames "Ancestor"])</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Ornithine_carbamoyltransferase Ornithine carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.3 2.1.3.3] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nf2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nf2 RCSB], [http://www.ebi.ac.uk/pdbsum/4nf2 PDBsum]</td></tr>

</table>

==~~Function~~==

==See Also==

[[~~http://www.uniprot.org/uniprot/OTC_BACAN OTC_BACAN~~]] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109]

*[[Ornithine carbamoyltransferase|Ornithine carbamoyltransferase]]

__TOC__

~~==About this Structure==~~

</StructureSection>

[[~~4nf2]~~] ~~is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NF2 OCA~~].

[[Category: Bacillus anthracis ames ancestor]]

[[Category: Ornithine carbamoyltransferase]]

[[Category: Anderson, W F.]]

[[Category: Anderson, W F]]

[[Category: ~~CSGID, Center for~~ Structural ~~Genomics of Infectious Diseases.~~]]

[[Category: Structural genomic]]

[[Category: Cymborowski, M T.]]

[[Category: Cymborowski, M T]]

[[Category: Handing, K.]]

[[Category: Handing, K]]

[[Category: Minor, W.]]

[[Category: Minor, W]]

[[Category: Shabalin, I G.]]

[[Category: Shabalin, I G]]

[[Category: Shuvalova, L.]]

[[Category: Shuvalova, L]]

[[Category: Stam, J.]]

[[Category: Stam, J]]

[[Category: Winsor, J.]]

[[Category: Winsor, J]]

[[Category: Carbamoyl phosphate]]

~~[[Category: Center for structural genomics of infectious disease]]~~

[[Category: Csgid]]

[[Category: L-ornithine]]

[[Category: National institute of allergy and infectious disease]]

[[Category: Niaid]]

~~[[Category: Structural genomic]]~~

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4nf2|  PDB=4nf2  |  SCENE=  }}
+==Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline==
-===Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline===
+<StructureSection load='4nf2' size='340' side='right' caption='[[4nf2]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4nf2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_ames_"ancestor" Bacillus anthracis ames "ancestor"]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NF2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NF2 FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CP:PHOSPHORIC+ACID+MONO(FORMAMIDE)ESTER'>CP</scene>, <scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ep1|4ep1]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">argF, BAS4036, BA_4351, GBAA_4351 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=261594 Bacillus anthracis Ames "Ancestor"])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ornithine_carbamoyltransferase Ornithine carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.3 2.1.3.3] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nf2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nf2 RCSB], [http://www.ebi.ac.uk/pdbsum/4nf2 PDBsum]</span></td></tr>
+</table>
-==Function==
+==See Also==
-[[http://www.uniprot.org/uniprot/OTC_BACAN OTC_BACAN]] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109]
+*[[Ornithine carbamoyltransferase|Ornithine carbamoyltransferase]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[4nf2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NF2 OCA].
+[[Category: Bacillus anthracis ames ancestor]]
 [[Category: Ornithine carbamoyltransferase]]
-[[Category: Anderson, W F.]]
+[[Category: Anderson, W F]]
-[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
+[[Category: Structural genomic]]
-[[Category: Cymborowski, M T.]]
+[[Category: Cymborowski, M T]]
-[[Category: Handing, K.]]
+[[Category: Handing, K]]
-[[Category: Minor, W.]]
+[[Category: Minor, W]]
-[[Category: Shabalin, I G.]]
+[[Category: Shabalin, I G]]
-[[Category: Shuvalova, L.]]
+[[Category: Shuvalova, L]]
-[[Category: Stam, J.]]
+[[Category: Stam, J]]
-[[Category: Winsor, J.]]
+[[Category: Winsor, J]]
 [[Category: Carbamoyl phosphate]]
-[[Category: Center for structural genomics of infectious disease]]
 [[Category: Csgid]]
 [[Category: L-ornithine]]
 [[Category: National institute of allergy and infectious disease]]
 [[Category: Niaid]]
-[[Category: Structural genomic]]
 [[Category: Transferase]]