4lhr: Difference between revisions

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~~{{STRUCTURE_4lhr| PDB=4lhr | SCENE= }}~~

==Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis==

===Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis===

== Structural highlights ==

<table><tr><td colspan='2'>[[4lhr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_thailandensis_e264 Burkholderia thailandensis e264]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LHR OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LHR FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">BTH_I0767, dut ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=271848 Burkholderia thailandensis E264])</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lhr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lhr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lhr RCSB], [http://www.ebi.ac.uk/pdbsum/4lhr PDBsum]</td></tr>

</table>

==~~Function~~==

==See Also==

[[~~http://www.uniprot.org/uniprot/DUT_BURTA DUT_BURTA~~]] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity).

*[[Deoxyuridine 5'-triphosphate nucleotidohydrolase|Deoxyuridine 5'-triphosphate nucleotidohydrolase]]

__TOC__

~~==About this Structure==~~

</StructureSection>

[[4lhr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_thailandensis_e264 Burkholderia thailandensis e264]. Full crystallographic information is available from [http://oca.weizmann.ac.il/~~oca-bin/ocashort?id=4LHR OCA].~~

[[Category: Burkholderia thailandensis e264]]

[[Category: DUTP diphosphatase]]

[[Category: ~~SSGCID, Seattle~~ Structural ~~Genomics Center for Infectious Disease.~~]]

[[Category: Structural genomic]]

[[Category: Hydrolase]]

[[Category: National institute of allergy and infectious disease]]

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[[Category: Nucleotide metabolism]]

[[Category: Pyrimidine]]

~~[[Category: Seattle structural genomics center for infectious disease]]~~

[[Category: Ssgcid]]

~~[[Category: Structural genomic]]~~

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4lhr|  PDB=4lhr  |  SCENE=  }}
+==Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis==
-===Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis===
+<StructureSection load='4lhr' size='340' side='right' caption='[[4lhr]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4lhr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_thailandensis_e264 Burkholderia thailandensis e264]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LHR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LHR FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BTH_I0767, dut ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=271848 Burkholderia thailandensis E264])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lhr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lhr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lhr RCSB], [http://www.ebi.ac.uk/pdbsum/4lhr PDBsum]</span></td></tr>
+</table>
-==Function==
+==See Also==
-[[http://www.uniprot.org/uniprot/DUT_BURTA DUT_BURTA]] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity).
+*[[Deoxyuridine 5'-triphosphate nucleotidohydrolase|Deoxyuridine 5'-triphosphate nucleotidohydrolase]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[4lhr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_thailandensis_e264 Burkholderia thailandensis e264]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LHR OCA].
 [[Category: Burkholderia thailandensis e264]]
 [[Category: DUTP diphosphatase]]
-[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
+[[Category: Structural genomic]]
 [[Category: Hydrolase]]
 [[Category: National institute of allergy and infectious disease]]
@@ Line 15: / Line 21: @@
 [[Category: Nucleotide metabolism]]
 [[Category: Pyrimidine]]
-[[Category: Seattle structural genomics center for infectious disease]]
 [[Category: Ssgcid]]
-[[Category: Structural genomic]]