4nhd: Difference between revisions

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{{STRUCTURE_4nhd|  PDB=4nhd  |  SCENE=  }}
==Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Vibrio Cholerae in complex with Coenzyme A==
===Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Vibrio Cholerae in complex with Coenzyme A===
<StructureSection load='4nhd' size='340' side='right' caption='[[4nhd]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[4nhd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibch Vibch]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NHD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NHD FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/FABH1_VIBCH FABH1_VIBCH]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids (By similarity).
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
 
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SCY:S-ACETYL-CYSTEINE'>SCY</scene></td></tr>
==About this Structure==
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabH1, VC2023, VC_2023 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243277 VIBCH])</td></tr>
[[4nhd]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NHD OCA].  
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_III Beta-ketoacyl-[acyl-carrier-protein] synthase III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.180 2.3.1.180] </span></td></tr>
[[Category: Anderson, W F.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nhd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nhd RCSB], [http://www.ebi.ac.uk/pdbsum/4nhd PDBsum]</span></td></tr>
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
</table>
[[Category: Hou, J.]]
__TOC__
[[Category: Langner, K.]]
</StructureSection>
[[Category: Minor, W.]]
[[Category: Vibch]]
[[Category: Zheng, H.]]
[[Category: Anderson, W F]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Structural genomic]]
[[Category: Hou, J]]
[[Category: Langner, K]]
[[Category: Minor, W]]
[[Category: Zheng, H]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Vibrio cholerae]]
[[Category: Vibrio cholerae]]

Revision as of 16:12, 21 December 2014

Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Vibrio Cholerae in complex with Coenzyme A

4nhd, resolution 1.78Å

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