1sm2: Difference between revisions

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[[Image:1sm2.jpg|left|200px]]<br /><applet load="1sm2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1sm2.jpg|left|200px]]
caption="1sm2, resolution 2.3&Aring;" />
 
'''Crystal structure of the phosphorylated Interleukin-2 tyrosine kinase catalytic domain'''<br />
{{Structure
|PDB= 1sm2 |SIZE=350|CAPTION= <scene name='initialview01'>1sm2</scene>, resolution 2.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=STU:STAUROSPORINE'>STU</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE= ITK, LYK, EMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the phosphorylated Interleukin-2 tyrosine kinase catalytic domain'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1SM2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=STU:'>STU</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SM2 OCA].  
1SM2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SM2 OCA].  


==Reference==
==Reference==
Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors., Brown K, Long JM, Vial SC, Dedi N, Dunster NJ, Renwick SB, Tanner AJ, Frantz JD, Fleming MA, Cheetham GM, J Biol Chem. 2004 Apr 30;279(18):18727-32. Epub 2004 Feb 6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14766749 14766749]
Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors., Brown K, Long JM, Vial SC, Dedi N, Dunster NJ, Renwick SB, Tanner AJ, Frantz JD, Fleming MA, Cheetham GM, J Biol Chem. 2004 Apr 30;279(18):18727-32. Epub 2004 Feb 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14766749 14766749]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: protein kinase]]
[[Category: protein kinase]]


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