1sme: Difference between revisions

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[[Image:1sme.gif|left|200px]]<br /><applet load="1sme" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1sme.gif|left|200px]]
caption="1sme, resolution 2.70&Aring;" />
 
'''PLASMEPSIN II, A HEMOGLOBIN-DEGRADING ENZYME FROM PLASMODIUM FALCIPARUM, IN COMPLEX WITH PEPSTATIN A'''<br />
{{Structure
|PDB= 1sme |SIZE=350|CAPTION= <scene name='initialview01'>1sme</scene>, resolution 2.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=IHN:3-HYDROXY-4-ISOBUTYL-4-[AMINOCARBONYLETHYL(AMINO CARBONYL-2-HYDROXY-5-METHYLHEXYL)TRI(AMINOCARBONYL ISOBUTYL)]BUTANOIC ACID'>IHN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39]
|GENE=
}}
 
'''PLASMEPSIN II, A HEMOGLOBIN-DEGRADING ENZYME FROM PLASMODIUM FALCIPARUM, IN COMPLEX WITH PEPSTATIN A'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1SME is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum] with <scene name='pdbligand=IHN:'>IHN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SME OCA].  
1SME is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SME OCA].  


==Reference==
==Reference==
Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum., Silva AM, Lee AY, Gulnik SV, Maier P, Collins J, Bhat TN, Collins PJ, Cachau RE, Luker KE, Gluzman IY, Francis SE, Oksman A, Goldberg DE, Erickson JW, Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10034-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8816746 8816746]
Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum., Silva AM, Lee AY, Gulnik SV, Maier P, Collins J, Bhat TN, Collins PJ, Cachau RE, Luker KE, Gluzman IY, Francis SE, Oksman A, Goldberg DE, Erickson JW, Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10034-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8816746 8816746]
[[Category: Plasmepsin II]]
[[Category: Plasmepsin II]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
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[[Category: hydrolase]]
[[Category: hydrolase]]


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