1stx: Difference between revisions

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[[Image:1stx.gif|left|200px]]<br /><applet load="1stx" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1stx.gif|left|200px]]
caption="1stx, resolution 2.10&Aring;" />
 
'''Structure of the K38A mutant of EcoRV bound to cognate DNA and Mn2+'''<br />
{{Structure
|PDB= 1stx |SIZE=350|CAPTION= <scene name='initialview01'>1stx</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE (II) ION'>MN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4]
|GENE= ECORVR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Structure of the K38A mutant of EcoRV bound to cognate DNA and Mn2+'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1STX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MN:'>MN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1STX OCA].  
1STX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1STX OCA].  


==Reference==
==Reference==
DNA cleavage by EcoRV endonuclease: two metal ions in three metal ion binding sites., Horton NC, Perona JJ, Biochemistry. 2004 Jun 8;43(22):6841-57. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15170321 15170321]
DNA cleavage by EcoRV endonuclease: two metal ions in three metal ion binding sites., Horton NC, Perona JJ, Biochemistry. 2004 Jun 8;43(22):6841-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15170321 15170321]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: restriction enzyme; ecorv; dna; x-ray crystallography]]
[[Category: restriction enzyme; ecorv; dna; x-ray crystallography]]


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