4kzi: Difference between revisions

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{{STRUCTURE_4kzi|  PDB=4kzi  |  SCENE=  }}
==Crystal Structure of TR3 LBD in complex with DPDO==
===Crystal Structure of TR3 LBD in complex with DPDO===
<StructureSection load='4kzi' size='340' side='right' caption='[[4kzi]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[4kzi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KZI FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZJ0:1-(3,5-DIMETHOXYPHENYL)DECAN-1-ONE'>ZJ0</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kzj|4kzj]], [[4kzm|4kzm]], [[4jgv|4jgv]]</td></tr>
==About this Structure==
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GFRP1, HMR, NAK1, NR4A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
[[4kzi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZI OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kzi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kzi RCSB], [http://www.ebi.ac.uk/pdbsum/4kzi PDBsum]</span></td></tr>
 
</table>
==Reference==
__TOC__
<references group="xtra"/><references/>
</StructureSection>
[[Category: Cai, Q.]]
[[Category: Human]]
[[Category: Chen, H.]]
[[Category: Cai, Q]]
[[Category: Li, A.]]
[[Category: Chen, H]]
[[Category: Li, F.]]
[[Category: Li, A]]
[[Category: Lin, T.]]
[[Category: Li, F]]
[[Category: Tian, X.]]
[[Category: Lin, T]]
[[Category: Wang, W.]]
[[Category: Tian, X]]
[[Category: Wang, Y.]]
[[Category: Wang, W]]
[[Category: Wu, Q.]]
[[Category: Wang, Y]]
[[Category: Xing, Y.]]
[[Category: Wu, Q]]
[[Category: Zhang, Q.]]
[[Category: Xing, Y]]
[[Category: Zhang, Q]]
[[Category: Orphan nuclear receptor]]
[[Category: Orphan nuclear receptor]]
[[Category: Transcription]]
[[Category: Transcription]]

Revision as of 17:44, 21 December 2014

Crystal Structure of TR3 LBD in complex with DPDO

4kzi, resolution 2.41Å

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