1szu: Difference between revisions

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[[Image:1szu.gif|left|200px]]<br /><applet load="1szu" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1szu.gif|left|200px]]
caption="1szu, resolution 2.52&Aring;" />
 
'''The structure of gamma-aminobutyrate aminotransferase mutant: V241A'''<br />
{{Structure
|PDB= 1szu |SIZE=350|CAPTION= <scene name='initialview01'>1szu</scene>, resolution 2.52&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene> and <scene name='pdbligand=PMP:4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE'>PMP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/4-aminobutyrate_transaminase 4-aminobutyrate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.19 2.6.1.19]
|GENE= GABT, B2662 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''The structure of gamma-aminobutyrate aminotransferase mutant: V241A'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1SZU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=EDO:'>EDO</scene>, <scene name='pdbligand=PLP:'>PLP</scene> and <scene name='pdbligand=PMP:'>PMP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/4-aminobutyrate_transaminase 4-aminobutyrate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.19 2.6.1.19] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZU OCA].  
1SZU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZU OCA].  


==Reference==
==Reference==
Kinetic and crystallographic analysis of active site mutants of Escherichia coli gamma-aminobutyrate aminotransferase., Liu W, Peterson PE, Langston JA, Jin X, Zhou X, Fisher AJ, Toney MD, Biochemistry. 2005 Mar 1;44(8):2982-92. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15723541 15723541]
Kinetic and crystallographic analysis of active site mutants of Escherichia coli gamma-aminobutyrate aminotransferase., Liu W, Peterson PE, Langston JA, Jin X, Zhou X, Fisher AJ, Toney MD, Biochemistry. 2005 Mar 1;44(8):2982-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15723541 15723541]
[[Category: 4-aminobutyrate transaminase]]
[[Category: 4-aminobutyrate transaminase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: gaba-at]]
[[Category: gaba-at]]


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