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{{STRUCTURE_3zlf|  PDB=3zlf  |  SCENE=  }}
==Structure of group A Streptococcal enolase K312A mutant==
===Structure of group A Streptococcal enolase K312A mutant===
<StructureSection load='3zlf' size='340' side='right' caption='[[3zlf]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3zlf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Strp6 Strp6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZLF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zlg|3zlg]], [[3zlh|3zlh]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [http://www.ebi.ac.uk/pdbsum/3zlf PDBsum]</span></td></tr>
</table>


==Function==
==See Also==
[[http://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref> 
*[[Enolase|Enolase]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3zlf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA].
 
==Reference==
<references group="xtra"/><references/>
[[Category: Phosphopyruvate hydratase]]
[[Category: Phosphopyruvate hydratase]]
[[Category: Aquilina, J A.]]
[[Category: Strp6]]
[[Category: Bertozzi, C.]]
[[Category: Aquilina, J A]]
[[Category: Casey, L W.]]
[[Category: Bertozzi, C]]
[[Category: Cork, A J.]]
[[Category: Casey, L W]]
[[Category: Ericsson, D J.]]
[[Category: Cork, A J]]
[[Category: Kobe, B.]]
[[Category: Ericsson, D J]]
[[Category: Law, R H.P.]]
[[Category: Kobe, B]]
[[Category: Stamp, A.]]
[[Category: Law, R H.P]]
[[Category: Valkov, E.]]
[[Category: Stamp, A]]
[[Category: Walker, M J.]]
[[Category: Valkov, E]]
[[Category: Whisstock, J C.]]
[[Category: Walker, M J]]
[[Category: Whisstock, J C]]
[[Category: Lyase]]
[[Category: Lyase]]
[[Category: Plasminogen-binding]]
[[Category: Plasminogen-binding]]

Revision as of 18:34, 21 December 2014

Structure of group A Streptococcal enolase K312A mutant

3zlf, resolution 2.15Å

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