1t37: Difference between revisions

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[[Image:1t37.gif|left|200px]]<br /><applet load="1t37" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1t37.gif|left|200px]]
caption="1t37, resolution 2.60&Aring;" />
 
'''Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between group I phospholipase A2 and a designed pentapeptide Leu-Ala-Ile-Tyr-Ser at 2.6A resolution'''<br />
{{Structure
|PDB= 1t37 |SIZE=350|CAPTION= <scene name='initialview01'>1t37</scene>, resolution 2.60&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ACT:ACETATE ION'>ACT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4]
|GENE=
}}
 
'''Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between group I phospholipase A2 and a designed pentapeptide Leu-Ala-Ile-Tyr-Ser at 2.6A resolution'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1T37 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera] with <scene name='pdbligand=ACT:'>ACT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T37 OCA].  
1T37 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T37 OCA].  


==Reference==
==Reference==
Crystal structure of the complex of group I PLA2 with a group II-specific peptide Leu-Ala-Ile-Tyr-Ser (LAIYS) at 2.6 A resolution., Singh RK, Singh N, Jabeen T, Sharma S, Dey S, Singh TP, J Drug Target. 2005 Jul;13(6):367-74. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16278156 16278156]
Crystal structure of the complex of group I PLA2 with a group II-specific peptide Leu-Ala-Ile-Tyr-Ser (LAIYS) at 2.6 A resolution., Singh RK, Singh N, Jabeen T, Sharma S, Dey S, Singh TP, J Drug Target. 2005 Jul;13(6):367-74. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16278156 16278156]
[[Category: Naja sagittifera]]
[[Category: Naja sagittifera]]
[[Category: Phospholipase A(2)]]
[[Category: Phospholipase A(2)]]
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[[Category: phospholipase a2]]
[[Category: phospholipase a2]]


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