2m2b: Difference between revisions
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==NMR structure of the RRM2 domain of the protein RBM10 from Homo sapiens== | |||
<StructureSection load='2m2b' size='340' side='right' caption='[[2m2b]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2m2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M2B FirstGlance]. <br> | |||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBM10, DXS8237E, GPATC9, GPATCH9, KIAA0122 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m2b RCSB], [http://www.ebi.ac.uk/pdbsum/2m2b PDBsum]</span></td></tr> | |||
</table> | |||
== | == Disease == | ||
[[2m2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M2B OCA]. | [[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] TARP syndrome. TARP syndrome (TARPS) [MIM:[http://omim.org/entry/311900 311900]]: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20451169</ref> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).<ref>PMID:18315527</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Dutta, S K | [[Category: Dutta, S K]] | ||
[[Category: Fox, B G | [[Category: Fox, B G]] | ||
[[Category: Geralt, M | [[Category: Geralt, M]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: MPP, Mitochondrial Protein Partnership | [[Category: MPP, Mitochondrial Protein Partnership]] | ||
[[Category: Makino, S | [[Category: Makino, S]] | ||
[[Category: Markley, J L | [[Category: Markley, J L]] | ||
[[Category: Misenhiemer, T M | [[Category: Misenhiemer, T M]] | ||
[[Category: Serrano, P | [[Category: Serrano, P]] | ||
[[Category: TCELL, Partnership for T-Cell Biology | [[Category: TCELL, Partnership for T-Cell Biology]] | ||
[[Category: Wrobel, R L | [[Category: Wrobel, R L]] | ||
[[Category: Wuthrich, K | [[Category: Wuthrich, K]] | ||
[[Category: Jcsg]] | [[Category: Jcsg]] | ||
[[Category: Mpp]] | [[Category: Mpp]] | ||
Revision as of 04:51, 22 December 2014
NMR structure of the RRM2 domain of the protein RBM10 from Homo sapiens
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